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Scholar Results 1 - 10 of about 19 citing Serino: Mice Heterozygous for Tumor Necrosis Factor-α Converting Enzyme Are Protected From.... (0.11 sec) 

TNF-α and adipocyte biology


WP Cawthorn, JK Sethi - FEBS letters, 2008 - Elsevier
Dyslipidemia and insulin resistance are commonly associated with catabolic or lipodystrophic
conditions (such as cancer and sepsis) and with pathological states of nutritional overload (such
as obesity-related type 2 diabetes). Two common features of these metabolic disorders ...
Cited by 40 - Related articles - All 12 versions

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo


JM Zabolotny, YB Kim, LA Welsh, EE Kershaw, BG … - Journal of Biological …, 2008 - ASBMB
Protein-tyrosine phosphatase 1B (PTP1B) is a major negative regulator of insulin and leptin
sensitivity. PTP1B overexpression in adipose tissue and skeletal muscle of humans and rodents
may contribute to insulin resistance and obesity. The mechanisms mediating PTP1B ...
Cited by 16 - Related articles - All 9 versions

Insulin resistance associated to obesity: the link TNF-alpha


I Nieto-Vazquez, S Fernandez-Veledo, DK … - … of Physiology and …, 2008 - informahealthcare.com
Adipose tissue secretes proteins which may influence insulin sensitivity. Among them, tumour
necrosis factor (TNF)-alpha has been proposed as a link between obesity and insulin resistance
because TNF-alpha is overexpressed in adipose tissue from obese animals and humans, ...
Cited by 12 - Related articles - All 5 versions

ADAM17 as a therapeutic target in multiple diseases


J Arribas, C Esselens - Current Pharmaceutical Design, 2009 - ingentaconnect.com
Abstract: As a metalloproteinase specialized in releasing membrane-tethered proteins, A Disintegrin
and A Metalloproteinase 17 (ADAM17), also known as Tumor necrosis factor- Converting Enzyme
(TACE) or less commonly CD156q, has received more than its share of attention. This is ...
Cited by 3 - Related articles - All 2 versions

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and …


R Menghini, S Menini, R Amoruso, L Fiorentino, V … - Gastroenterology, 2009 - Elsevier
Obesity-driven, low-grade inflammation affects systemic metabolic function and can lead to insulin
resistance, hepatic steatosis, and atherosclerosis. Decreased expression of tissue inhibitor of
metalloproteinase 3 (Timp3) is a catalyst for insulin resistance and inflammation. Timp3 is ...
Cited by 4 - Related articles - All 3 versions

Deficiency of TNF {alpha} Converting Enzyme (TACE/ADAM17) Causes a Lean, …


RW Gelling, W Yan, S Al-Noori, A Pardini, GJ Morton, K … - Endocrinology, 2008 - Endocrine Soc
Energy homeostasis involves central nervous system integration of afferent inputs that coordinately
regulate food intake and energy expenditure. Here, we report that adult homozygous TNF converting
enzyme (TACE)-deficient mice exhibit one of the most dramatic examples of ...
Cited by 2 - Related articles - All 4 versions

Time Course of Changes in the Expression of Insulin Sensitivity-Related Genes …


V Konstantinidou, O Khymenets, MI Covas, R de … - OMICS A Journal of … - liebertonline.com
Page 1. Time Course of Changes in the Expression of Insulin Sensitivity-Related
Genes after an Acute Load of Virgin Olive Oil Valentini Konstantinidou, 1 Olha
Khymenets, 2 Maria-Isabel Covas, 1 Rafael de la Torre, 2,3 Daniel ...
Cited by 2 - Related articles - All 3 versions

Getting the message across: mechanisms of physiological cross talk by adipose …


DE Lee, S Kehlenbrink, H Lee, M Hawkins … - American Journal of …, 2009 - Am Physiological Soc
Obesity is associated with resistance of skeletal muscle to insulin-mediated glucose uptake,
as well as resistance of different organs and tissues to other metabolic and vascular actions of
insulin. In addition, the body is exquisitely sensitive to nutrient imbalance, with energy ...
Cited by 1 - Related articles - All 3 versions

GENETIC CHARACTERIZATION OF THE ST. KITTS-ORIGIN VERVET MONKEY ( …

- wfu.edu [PDF] 
S Gray - 2009 - wakespace.lib.wfu.edu
Page 1. 1 GENETIC CHARACTERIZATION OF THE ST. KITTS-ORIGIN VERVET
MONKEY (CHLOROCEBUS AETHIOPS SSP.) AS A MODEL OF POLYGENIC OBESITY
BY STANTON BRADLEY GRAY, DVM A Dissertation Submitted ...
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Molecular mechanisms involved in obesity-associated insulin resistance: …


S Fernandez-Veledo, I Nieto-Vazquez, R … - … of Physiology and …, 2009 - ingentaconnect.com
Insulin resistance is an important contributor to the pathogenesis of type 2 diabetes (T2D) and
obesity is a risk factor for its development. In the obese state an altered secretion pattern, with
increase in pro- inflammatory and decrease in anti-inflammatory factors is found ...
Related articles - All 4 versions


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