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Scholar Results 1 - 10 of about 16 citing Kwan: Interaction Between Munc13-1 and RIM Is Critical for Glucagon-Like Peptide-1–Mediated.... (0.08 sec) 

SNAREing Voltage-Gated K+ and ATP-Sensitive K+ Channels: Tuning {beta}-Cell …

- endojournals.org
YM Leung, EP Kwan, B Ng, Y Kang, HY Gaisano - Endocrine reviews, 2007 - Endocrine Soc
The three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor)
proteins, syntaxin, SNAP25 (synaptosome-associated protein of 25 kDa), and
synaptobrevin, constitute the minimal machinery for exocytosis in secretory cells such as ...
Cited by 16 - Related articles - BL Direct - All 3 versions

Application of an Epac activator enhances neurotransmitter release at excitatory …

- jneurosci.org
I Gekel, E Neher - Journal of Neuroscience, 2008 - Soc Neuroscience
Greengard et al. (1970) Go showed that neuronal activity increases cAMP levels in superior cervical
ganglia. At excitatory mammalian cerebral synapses, cAMP is known to enhance glutamate release
from presynaptic terminals (Weisskopf et al., 1994 Go ; Leßmann and Heumann, 1997 Go ...
Cited by 12 - Related articles - All 3 versions

The role of incretins in glucose homeostasis and diabetes treatment

- nih.gov
W Kim, JM Egan - Pharmacological reviews, 2008 - ASPET
Cited by 12 - Related articles - All 5 versions

The RalA GTPase Is a Central Regulator of Insulin Exocytosis from Pancreatic Islet …

- jbc.org
JA Lopez, EP Kwan, L Xie, Y He, DE James, HY … - Journal of Biological …, 2008 - ASBMB
RalA is a small GTPase that is thought to facilitate exocytosis through its direct interaction with
the mammalian exocyst complex. In this study, we report an essential role for RalA in regulated
insulin secretion from pancreatic beta cells. We employed lentiviral-mediated delivery of ...
Cited by 5 - Related articles - All 3 versions

EPAC proteins transduce diverse cellular actions of cAMP


G Borland, BO Smith, SJ Yarwood - British Journal of …, 2009 - interscience.wiley.com
It has now been over 10 years since efforts to completely understand the signalling actions of
cAMP (3'-5'-cyclic adenosine monophosphate) led to the discovery of exchange protein directly
activated by cAMP (EPAC) proteins. In the current review we will highlight important ...
Cited by 4 - Related articles - All 4 versions

JBC Papers in Press. Published on April 21, 2008 as Manuscript M800321200


JA Lopez, EP Kwan, L Xie, Y He, DE James, HY … - Journal of Biological … - ASBMB
From the 1 Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney,
NSW, Australia 2010 and the 2 Department of Physiology and Medicine, University of
Toronto, Toronto, Ontario, Canada M5S 1A8 ... *The authors contributed equally to this ...
Related articles

SNAREing Kv and KATP channels: Tuning {beta}-Cell Excitability with Syntaxin-1A …

- endojournals.org [PDF] 
YM Leung, EP Kwan, B Ng, Y Kang, HY Gaisano - Endocrine Reviews, 2007 - Endocrine Soc
1 Department of Physiology, China Medical University, Taichung 40402, Taiwan 2 Graduate
Institute of Neural and Cognitive Sciences, China Medical University, Taichung 40402, Taiwan
3 Departments of Medicine and Physiology, University of Toronto, Toronto, Canada
Related articles

JBC Papers in Press. Published on June 1, 2009 as Manuscript M109. 017467


Y Zhang, Y Kang, N Chang, PPL Lam, Y Liu, VM … - ASBMB
1Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario, Canada M5S
1A8, 2National Institute for Health and Welfare and FIMM, Institute for Molecular Medicine
Finland, Univ. of Helsinki, Biomedicum, POBox 104, FI-00251 Helsinki, Finland
Related articles

Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis …


J Vikman, H Svensson, YC Huang, Y … - American Journal of …, 2009 - Am Physiological Soc
Synaptosomal protein of 25 kDa (SNAP-25) is important for Ca 2+ -dependent fusion of large
dense core vesicles (LDCVs) in insulin-secreting cells. Exocytosis is further enhanced by
cAMP-increasing agents such as glucagon-like peptide-1 (GLP-1), and this augmentation ...
Related articles - All 3 versions

Role of cyclic AMP signaling in the production and function of the incretin hormone …

- nsfc.gov.cn [PDF] 
Z Yu, T Jin - Science Foundation in China, 2008 - iop.org
Pancreatic cells express the proglucagon gene (gcg) and thereby produce the peptide hormone
glucagon, which stimulates hepatic glucose produc tion and thereby increases blood glucose
levels. The same gcg gene is also expressed in the intesti nal endocrine L cells and ...
Related articles - All 4 versions


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