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Scholar Results 1 - 10 of about 20 citing Obrosova: High-Fat Diet–Induced Neuropathy of Pre-Diabetes and Obesity. (0.18 sec) 

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and …


IG Obrosova, W Xu, VV Lyzogubov, O Ilnytska, … - Free Radical Biology and Medicine, 2008 - Elsevier
Evidence that poly(ADP-ribose) polymerase (PARP) activation plays an important
role in diabetic complications is emerging. This study evaluated the role of
PARP in rat and mouse models of advanced diabetic neuropathy. The orally ...
Cited by 15 - Related articles - All 3 versions

Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin- …

- physiology.org
IG Obrosova, VR Drel, CL Oltman, N Mashtalir … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Evidence for important roles of the highly reactive oxidant peroxynitrite in
diabetic complications is emerging. We evaluated the role of peroxynitrite in
early peripheral neuropathy and vascular dysfunction in STZ-diabetic rats. ...
Cited by 16 - Related articles - BL Direct - All 5 versions

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin- …


VR Drel, P Pacher, I Vareniuk, I Pavlov, O … - European journal of pharmacology, 2007 - pubmedcentral.nih.gov
Whereas an important role of free radicals and oxidants in peripheral diabetic
neuropathy is well established, the contribution of nitrosative stress and, in
particular, of the highly reactive oxidant peroxynitrite, has not been ...
Cited by 13 - Related articles - All 6 versions

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy


C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer
Abstract Diabetic neuropathy is the most common com- plication of diabetes,
affecting 50% of diabetic patients. Currently, the only treatment for diabetic
neuropathy is glucose control and careful foot care. In this review, we ...
Cited by 11 - Related articles - All 2 versions

Pro-inflammatory mechanisms in diabetic neuropathy: focus on the nuclear factor kappa B …


NE Cameron, MA Cotter - Current Drug Targets, 2008 - ingentaconnect.com
Abstract: Neuropathy is a common complication of diabetes mellitus, which
reduces the quality of life and may be life- threatening. The etiology is
complex and multifactorial: hyperglycemia and dyslipidemia give rise to ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of …

- pbrc.edu [PDF] 
I Vareniuk, IA Pavlov, IG Obrosova - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Evidence for the importance of peroxyni- trite, a
product of superoxide anion radical reaction with nitric oxide, in peripheral
diabetic neuropathy is emerging. The role of specific nitric oxide synthase ...
Cited by 4 - Related articles - All 5 versions

Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic …


KK Beiswenger, NA Calcutt, AP Mizisin - Neuroscience Letters, 2008 - Elsevier
The quantification of epidermal innervation, which consists primarily of
heat-sensitive C-fibers, is emerging as a tool for diagnosing and staging
diabetic neuropathy. However, the relationship between changes in heat ...
Cited by 3 - Related articles - All 2 versions

5-Lipoxygenase, but not 12/15-Lipoxygenase, contributes to degeneration of retinal …

- diabetesjournals.org
RA Gubitosi-Klug, R Talahalli, Y Du, JL … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Diabetic wild-type mice developed the expected degeneration of retinal
capillaries and pericytes and increases in both leukostasis and superoxide
production (P < 0.006). We found no evidence of diabetes-induced ...
Cited by 3 - Related articles - BL Direct - All 4 versions

Criteria for creating and assessing mouse models of diabetic neuropathy


EL Feldman, KA Sullivan, SI Lentz, JL Roberts … - Current Drug Targets, 2008 - ingentaconnect.com
Abstract: Diabetic neuropathy (DN) is a serious and debilitating complication of
both type 1 and type 2 diabetes. Despite intense research efforts into multiple
aspects of this complication, including both vascular and neuronal ...
Cited by 3 - Related articles - BL Direct - All 2 versions

The effects of high fat on central appetite genes in Wistar rats: A microarray analysis


R Xu, Y Wan, Q Tang, J Wu, W Cai - Clinica Chimica Acta, 2008 - Elsevier
Body weight increased significantly in HF group compared with control group,
whereas energy intake was similar in the two groups. HF had a time dependent
effect on plasma leptin, but insulin and ghrelin level remained stable ...
Cited by 3 - Related articles - All 3 versions


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