- ►nih.gov MCY Ng, KS Park, B Oh, CHT Tam, YM Cho, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— We confirmed the associations of TCF7L2, SLC30A8, HHEX, CDKAL1,
CDKN2A/CDKN2B, IGF2BP2, and FTO with risk for type 2 diabetes, with odds ratios
ranging from 1.13 to 1.35 (1.3 × 10 −12 < P unadjusted < 0.016). In ... Cited by 51 - Related articles - All 4 versions
- ►pubget.com [PDF] H Li, Y Wu, RJF Loos, FB Hu, Y Liu, J Wang, Z … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The minor allele frequencies of rs8050136, rs9939609, and rs9930506
in our population (0.12, 0.12, and 0.20, respectively) were substantially lower
than those observed for populations of European descent (eg, for CEU ... Cited by 48 - Related articles - BL Direct - All 5 versions
JC Florez - Diabetologia, 2008 - Springer Abstract Although type 2 diabetes has been traditionally understood as a
metabolic disorder initiated by insulin resistance, it has recently become
apparent that an impairment in insulin secretion contributes to its mani- ... Cited by 31 - Related articles - BL Direct - All 3 versions
K Miyake, Y Horikawa, K Hara, K Yasuda, H … - Journal of Human Genetics, 2008 - Springer Abstract Transcription factor 7-like 2 (TCF7L2) has been shown to be associated
with type 2 diabetes mellitus in multiple ethnic groups. Regarding the Asian
population, Horikoshi et al. (Diabetologia 50:747–751, 2007) and Hayashi ... Cited by 21 - Related articles - BL Direct - All 3 versions
S Cauchi, P Froguel - Current Diabetes Reports, 2008 - Springer After two decades of limited success, the genetic architecture of type 2
diabetes (T2D) is finally being revealed. Within only 2 years, an avalanche of
studies identified several genes expressed in pancreatic ß cells and ... Cited by 13 - Related articles - BL Direct - All 2 versions
JCN Chan, V Malik, W Jia, T Kadowaki, CS … - Jama, 2009 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do
to make your experience on this site better. ... Add to CiteULike Add to ... Cited by 12 - Related articles - All 4 versions
T Jin - Diabetologia, 2008 - Springer Abstract The WNT signalling pathway is involved in many physiological and
pathophysiological activities. WNT ligands bind to Frizzled receptors and
co-receptors (LDL receptor-related protein 5/6), triggering a cascade of ... Cited by 12 - Related articles - All 3 versions
- ►phbjmu.edu.cn [PDF] Q Ren, XY Han, F Wang, XY Zhang, LC Han, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Recently, variants in the transcription factor 7-like 2
(TCF7L2) gene have been found to be consistently associated with type 2 diabetes
in different populations. In this study, we hypothesized that TCF7L2 also ... Cited by 11 - Related articles - BL Direct - All 5 versions
H Saadi, N Nagelkerke, SG Carruthers, S … - Diabetes Research and Clinical Practice, 2008 - Elsevier We genotyped the two TCF7L2 single nucleotide polymorphisms (SNPs) rs12255372
and rs7903146 in 368 adult subjects. Homeostatic model assessment (HOMA) was
used to assess beta cell function (HOMA2-%B) and insulin resistance ... Cited by 6 - Related articles - All 14 versions
- ►endojournals.org T Jin, L Liu - Molecular Endocrinology, 2008 - Endocrine Soc Since the relationship between TCF7L2 (also known as TCF-4) polymorphisms and
type 2 diabetes mellitus was identified in 2006, extensive genome-wide
association examinations in different ethnic groups have further confirmed ... Cited by 6 - Related articles - All 4 versions