JP Lewis, ND Palmer, PJ Hicks, MM Sale, CD … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Several whole-genome association studies have reported identification of type
2 diabetes susceptibility genes in various European-derived study populations. Little investigation
of these loci has been reported in other ethnic groups, specifically African Americans. ... Cited by 17 - Related articles - All 10 versions
- ►diabetesjournals.org KL Keene, JC Mychaleckyj, SG Smith, TS Leak, PS … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Variants in the ectonucleotide pyrophosphatase/phosphodiesterase 1
(ENPP1) gene have shown positive associations with diabetes and related phenotypes, including
insulin resistance, metabolic syndrome, and type 1 diabetic nephropathy. Additionally, ... Cited by 9 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] JP Lewis, ND Palmer, PJ Hicks, MM Sale, CD … - Diabetes, 2008 - Am Diabetes Assoc WGA SNPs and diabetes in African Americans ... Association Analysis of European-Derived
Type 2 Diabetes SNPs from Whole Genome Association Studies in African Americans ... Joshua
P. Lewis 1,2 , Nicholette D. Palmer 1,3 , Pamela J. Hicks 1,3 , Michele M. Sale 4,5 , Carl D. Cited by 9 - Related articles - All 2 versions
- ►endojournals.org T Jin, L Liu - Molecular Endocrinology, 2008 - Endocrine Soc Since the relationship between TCF7L2 (also known as TCF-4) polymorphisms and type 2 diabetes
mellitus was identified in 2006, extensive genome-wide association examinations in different
ethnic groups have further confirmed this relationship. As a component of the bipartite ... Cited by 6 - Related articles - All 4 versions
- ►diabetesjournals.org MO Goodarzi, JI Rotter - Diabetes, 2007 - Am Diabetes Assoc Given that susceptibility to type 2 diabetes appears in large measure due to genetic makeup,
investigators have spent years of effort trying to identify genes that influence type 2 diabetes
risk. An important goal of gene identification is to improve our understanding of the ... Cited by 4 - Related articles - BL Direct - All 3 versions
- ►pubget.com [PDF] KL Keene, JC Mychaleckyj, TS Leak, SG Smith, PS … - Human Genetics, 2008 - Springer Abstract Admixture and population stratiWcation are major concerns in genetic association
studies. We wished to evaluate the impact of admixture using empirically derived data from genetic
association studies of African Americans (AA) with type 2 diabetes (T2DM) and end-stage ... Cited by 4 - Related articles - All 8 versions
DA Trégouet, PH Groop, S McGinn, C Forsblom, S … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Only one SNP, rs2281999, located in the UNC13B gene, was significantly associated
with nephropathy after correction for multiple testing. Analyses of 21 additional markers fully
characterizing the haplotypic variability of the UNC13B gene showed consistent ... Cited by 3 - Related articles - All 5 versions
- ►nih.gov TS Leak, JC Mychaleckyj, SG Smith, KL Keene, CJ … - Human genetics, 2008 - Springer Abstract Previously, we performed a genome scan for type 2 diabetes (T2DM) using 638
African-American (AA) affected sibling pairs from 247 families; non-parametric linkage analysis
suggested evidence of linkage at 6q24–27 (LOD 2.26). To comprehensively evaluate this ... Cited by 2 - Related articles - All 6 versions
MM Sale, L Lu, IJ Spruill, JK Fernandes, KH Lok, J … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Linkage peaks on chromosome 14 at 123–124 cM were detected for type 2 diabetes
(logarithm of odds [LOD] 2.10) and for the subset with later age at type 2 diabetes diagnosis
(maximum LOD 4.05). Two linkage peaks on chromosome 7 were detected at 44–45 cM ... Cited by 2 - Related articles - All 3 versions
