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Scholar Results 1 - 10 of about 24 citing Tang: Evidence for a role of superoxide generation in glucose-induced β-cell dysfunction in vivo. (0.09 sec) 

Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin


K Aston-Mourney, J Proietto, G Morahan, S … - Diabetologia, 2008 - Springer
Abstract In many countries, first- or second-line pharma- cological treatment of
patients with type 2 diabetes consists of sulfonylureas (such as glibenclamide
[known as glyburide in the USA and Canada]), which stimulate the beta cell ...
Cited by 11 - Related articles - BL Direct - All 3 versions

The intrauterine metabolic environment modulates the gene expression pattern in fetal rat …


B Reusens, T Sparre, L Kalbe, T Bouckenooghe, … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Events during fetal life may in critical time windows
programme tissue development leading to organ dysfunction with potentially
harmful consequences in adulthood such as diabetes. In rats, the beta cell ...
Cited by 4 - Related articles - BL Direct - All 3 versions

Upregulation of the heme oxygenase system ameliorates postprandial and fasting …


JF Ndisang, N Lane, A Jadhav - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
In type 2 diabetes (T2D), postprandial and fasting hyperglycemia are important
predictors of cardiovascular diseases; however, few drugs are currently
available to simultaneously suppress these conditions. Here, we report an ...
Cited by 4 - Related articles - All 4 versions

Heme oxygenase system enhances insulin sensitivity and glucose metabolism in …


JF Ndisang, A Jadhav - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
Hyperglycemia-induced oxidative stress is a common phenomenon in diabetes. Since
oxidative stress depletes adiponectin and insulin levels, we investigated
whether an upregulated heme oxygenase (HO) system would attenuate the ...
Cited by 4 - Related articles - All 3 versions

Up-Regulating the Hemeoxygenase System Enhances Insulin Sensitivity and Improves …


JF Ndisang, A Jadhav - Endocrinology, 2009 - Endocrine Soc
Insulin-mediated signal transduction is positively correlated to adiponectin,
adenosine monophosphate-activated protein kinase (AMPK), and
glucose-transporter-4 (GLUT4) but negatively to oxidative/inflammatory ...
Cited by 3 - Related articles - All 3 versions

Anti-oxidized low-density lipoprotein antibody levels are associated with the development of …


L Garrido-Sánchez, F Cardona, E García- … - European Journal of Clinical Investigation, 2008 - pt.wkhealth.com
Results: Of the women who were OGTT-N at the start of the study and who had
anti-oxidized LDL antibody levels below the 50th percentile, only 65·1% were
still OGTT-N after 6 years versus 79·5% of those who had anti-oxidized LDL ...
Cited by 3 - Related articles - All 5 versions

Fetal and neonatal nicotine exposure in Wistar rats causes progressive pancreatic …


JE Bruin, MA Petre, S Raha, KM Morrison, HC … - PLoS ONE, 2008 - pubmedcentral.nih.gov
Nicotine replacement therapy (NRT) is currently recommended as a safe smoking
cessation aid for pregnant women. However, fetal and neonatal nicotine exposure
in rats causes mitochondrial-mediated beta cell apoptosis at weaning, and ...
Cited by 2 - Related articles - All 6 versions

Glucose-modulated tyrosine nitration in beta cells: Targets and consequences

- ccf.org [PDF] 
T Koeck, JA Corbett, JW Crabb, DJ Stuehr, KS … - Archives of Biochemistry and Biophysics, 2009 - Elsevier
Hyperglycemia, key factor of the pre-diabetic and diabetic pathology, is
associated with cellular oxidative stress that promotes oxidative protein
modifications. We report that protein nitration is responsive to changes in ...
Cited by 1 - Related articles - All 6 versions

The Heme Oxygenase System Abates Hyperglycemia in Zucker Diabetic Fatty Rats by …


JF Ndisang… - Endocrinology, 2009 - Endocrine Soc
Emerging evidence indicates that aldosterone causes oxidative stress by
stimulating proinflammatory/oxidative mediators, including nuclear factor- B,
activating protein (AP-1), and c-Jun N-terminal kinase. Thus, in insulin- ...
Cited by 2 - Related articles - All 3 versions

Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes …


Z Zhang, J Jiang, P Yu, X Zeng, JW Larrick, … - Journal of Translational Medicine, 2009 - dx.doi.org
In alloxan-treated mice (a model of type 1 diabetes), drugs were administered
orally once daily for 6 days post-alloxan treatment. Fasting blood glucose and
serum insulin were determined. Pathologic and immunohistochemical analysis ...


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