KJ Chang-Chen, R Mullur, E Bernal-Mizrachi - Reviews in Endocrine & …, 2008 - Springer Abstract Type 2 diabetes mellitus is a complex disease characterized by b-cell failure in the setting
of insulin resistance. In early stages of the disease, pancreatic b-cells adapt to insulin resistance
by increasing mass and function. As nutrient excess persists, hyperglycemia and elevated ... Cited by 12 - Related articles - All 2 versions
C Schmitz-Peiffer, TJ Biden - Diabetes, 2008 - Am Diabetes Assoc Increased lipid availability is strongly associated with both β-cell dysfunction and insulin
resistance, two key facets of type 2 diabetes. Isoforms of the protein kinase C (PKC) family have
been viewed as candidates for mediating the effects of fat oversupply because they are ... Cited by 5 - Related articles - All 4 versions
A Assmann, C Hinault, RN Kulkarni, JD … - Pediatric Diabetes, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 3 - Related articles - All 3 versions
NM Fiaschi-Taesch, DM Berman, BM Sicari, KK Takane … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Baseline glucose values were 454.7 ± 11.3 mg/dl (n = 7). Transplant of 500 NHP
islet equivalents (IE) had only a marginal effect on blood glucose (369.1 ± 9.7 mg/dl, n = 5). In
striking contrast, 500 NHP IE transduced with Ad.mHGF promptly and continuously ... Cited by 2 - Related articles - All 5 versions
JA Lavine, PW Raess, DB Davis, ME Rabaglia, … - Molecular …, 2008 - Endocrine Soc Type 1 and type 2 diabetes result from a deficit in insulin production and β-cell mass. Methods
to expand β-cell mass are under intensive investigation for the treatment of type 1 and type 2
diabetes. We tested the hypothesis that cholecystokinin (CCK) can promote β-cell ... Cited by 2 - Related articles - All 3 versions
C Chen, TD Johnston, H Jeon, R Gedaly, P … - Journal of Surgical …, 2009 - Elsevier CsA (500 ng/mL) time dependently increased PKC-ζ from control of 7055 units to 7145,
10,805, 10,914, and 12,705 units, respectively, after 15 min, 1 h, 12 h, and 24 h of incubation
in EBV-transformed human B-cell line (LCL). CsA increased PKC-ζ expression was ... Cited by 1 - Related articles - All 26 versions
T Biden, C Schmitz-Peiffer, J Burchfield, E … - Biochemical Society …, 2008 - biochemsoctrans.org Members of the serine/threonine PKC (protein kinase C) family perform diverse functions in multiple
cell types. All members of the family are activated in signalling cascades triggered by occupation
of cell surface receptors, but the cPKC (conventional PKC) and nPKC (novel PKC) ... Cited by 1 - Related articles - Cached - All 3 versions