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Scholar Results 1 - 9 of 9 citing Puppala: Genotype by diabetes interaction effects on the detection of linkage of glomerular.... (0.10 sec) 

A genome-wide linkage scan for genes controlling variation in renal function …


G Placha, GD Poznik, J Dunn, A Smiles, B Krolewski, T … - Diabetes, 2006 - Am Diabetes Assoc
We performed a variance components linkage analysis of renal function, measured as glomerular
filtration rate (GFR), in 63 extended families with multiple members with type 2 diabetes. GFR
was estimated from serum concentrations of cystatin C and creatinine in 406 diabetic and ...
Cited by 30 - Related articles - BL Direct - All 5 versions

A genome-wide search for linkage to chronic kidney disease in a community-based …

- oxfordjournals.org
NH Arar, VS Voruganti, SD Nath, F Thameem, R … - Nephrology Dialysis …, 2008 - ERA-EDTA
Background. Chronic kidney disease (CKD) phenotypes such as albuminuria measured by urinary
albumin creatinine ratio (ACR), elevated serum creatinine (SrCr) and/or decreased creatinine
clearance (CrCl) and glomerular filtration rate (eGFR) are major risk factors for renal and ...
Cited by 6 - Related articles - All 6 versions

Genome-wide linkage analysis of serum creatinine in three isolated European …


C Pattaro, YS Aulchenko, A Isaacs, V Vitart, C … - Kidney International, 2009 - nature.com
Kidney International aims to inform the renal researcher and practicing nephrologists on all
aspects of renal research. Clinical and basic renal research, commentaries, The Renal Consult,
Nephrology sans Frontieres, minireviews, reviews, Nephrology Images, Journal Club. Published ...
Cited by 4 - Related articles - All 5 versions

The 27-bp repeat polymorphism in intron 4 (27 bp-VNTR) of endothelial nitric oxide …


SD Nath, X He, VS Voruganti, J Blangero, JW … - Molecular and Cellular … - Springer
Abstract The T-786C, Glu298Asp, and 27 bp variable numberoftandemrepeats(27
bp-VNTR-a/b)polymorphsims of the endothelial nitric oxide synthase (eNOS) gene are thought
to alter nitric oxide production and contribute to the development of vascular and renal ...
Related articles - All 2 versions

Genetic analysis of albuminuria in aging mice and concordance with loci for human …


SW Tsaih, MG Pezzolesi, R Yuan, JH Warram, AS … - Kidney International, 2009 - nature.com
Aging in the kidney can cause albuminuria, and discovering molecular mechanisms responsible
for this might offer a new perspective on the etiology of this abnormality. Haplotype association
mapping in the mouse is a novel approach which uses the haplotypes of the relatively ...

Quantitative genetics of renal function: tackling complexities of the eGFR …


K Kiryluk - Kidney International, 2008 - nature.com
The linkage approach to quantitative traits, such as estimated glomerular filtration rate
(eGFR), has been utilized in several recent studies aimed at identification of susceptibility
loci. However, the heterogeneity and complex architecture of the eGFR phenotype make ...
Cited by 2 - Related articles - All 4 versions

Unravelling the genetic basis of renal diseases; from single gene to multifactorial …


AJ McKnight, D Currie, AP Maxwell - The Journal of pathology, 2009 - interscience.wiley.com
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Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for …


F Thameem, S Puppala, X He, NH Arar, MP Stern, J … - Metabolism, 2009 - Elsevier
Several novel genes that are up-regulated in the kidney in diabetes have been identified including
GREM1, which encodes gremlin 1. GREM1 maps to human chromosome 15q12, a region previously
found to be linked to albumin to creatinine ratio (ACR) in Mexican Americans. The ...
Related articles - All 3 versions

Evaluation of Polymorphisms in Paraoxonase 2 (PON2) Gene and Their …


F Thameem, X He, VS Voruganti, SD Nath, P … - Kidney Blood Press …, 2009 - content.karger.com
Background/Aims: Genetic polymorphisms in the paraoxonase 2 (PON2) gene are thought to
alter its activity and contribute to the development of cardiovascular and renal disease risk. The
purpose of this study is to determine whether the Arg148Gly, Cys311Ser and rs12794795 ...
Related articles - All 4 versions


 


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