- ►diabetesjournals.org [PDF] JC Florez, AK Manning, J Dupuis, J McAteer, … - Diabetes, 2007 - Am Diabetes Assoc Page 1. A 100K Genome-Wide Association Scan for Diabetes and Related Traits in the
Framingham Heart Study Replication and Integration With Other Genome-Wide ... Cited by 33 - Related articles - BL Direct - All 4 versions
JC Florez - Diabetologia, 2008 - Springer Abstract Although type 2 diabetes has been traditionally understood as a
metabolic disorder initiated by insulin resistance, it has recently become
apparent that an impairment in insulin secretion contributes to its mani- ... Cited by 31 - Related articles - BL Direct - All 3 versions
MG Hayes, A Pluzhnikov, K Miyake, Y Sun, … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—We observed more significant allelic associations than expected genome
wide, as empirically assessed by permutation (14 below a P of 1 × 10 −4 [8.7
expected]). No significant differences were observed between the proportion ... Cited by 33 - Related articles - BL Direct - All 4 versions
S Cauchi, D Meyre, E Durand, C Proença, M … - PloS one, 2008 - pubmedcentral.nih.gov In the same French population analyzed in our previous GWA study (3,295 T2D and
3,595 NGT), strong associations with T2D were found for CDKAL1 (OR rs7756992 =
1.30[1.19–1.42], P = 2.3×10 −9 ), CDKN2A/2B (OR rs10811661 = ... Cited by 20 - Related articles - All 7 versions
- ►pubget.com [PDF] S Cauchi, C Proença, H Choquet, S Gaget, F … - Journal of Molecular Medicine, 2008 - Springer Page 1. RAPID COMMUNICATION Analysis of novel risk loci for type 2 diabetes
in a general French population: the DESIR study Stéphane ... Cited by 16 - Related articles - BL Direct - All 3 versions
- Free from Publisher Y Wang, JR O'Connell, PF McArdle, JB Wade, … - Proceedings of the National Academy of Sciences, 2009 - nihongo.j-talk.com Hypertension places a major burden on individual and public health, but the
genetic basis of this complex disorder is poorly understood. We conducted a
genome-wide association study of systolic and diastolic blood pressure (SBP ... Cited by 16 - Related articles - All 14 versions
- ►cell.com I Prokopenko, MI McCarthy, CM Lindgren - Trends in Genetics, 2008 - Elsevier Over the past two years, there has been a spectacular change in the capacity to
identify common genetic variants that contribute to predisposition to complex
multifactorial phenotypes such as type 2 diabetes (T2D). The principal ... Cited by 15 - Related articles - All 7 versions
- ►diabetesjournals.org KJ Gaulton, CJ Willer, Y Li, LJ Scott, KN … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—In a case-control study of 1,161 type 2 diabetic
subjects and 1,174 control Finns who are normal glucose tolerant, we genotyped
3,531 tagSNPs and annotation-based SNPs and imputed an additional 7,498 ... Cited by 12 - Related articles - All 6 versions
- ►geyseco.info [PDF] JC Florez - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Evidence Synthesis: As many as 17 genetic loci have been convincingly associated
with type 2 diabetes; 14 of these were not previously known, and most of them
were unsuspected. The associated polymorphisms are common in populations of ... Cited by 11 - Related articles - All 4 versions
