RL Hanson, C Bogardus, D Duggan, S Kobes, M … - Diabetes, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Data come from 300 case subjects with type 2
diabetes with age of onset <25 years and 334 nondiabetic control subjects aged
≥45 years. To provide for tests of within-family association, 121 ... Cited by 30 - Related articles - BL Direct - All 3 versions
K Miyake, Y Horikawa, K Hara, K Yasuda, H … - Journal of Human Genetics, 2008 - Springer Abstract Transcription factor 7-like 2 (TCF7L2) has been shown to be associated
with type 2 diabetes mellitus in multiple ethnic groups. Regarding the Asian
population, Horikoshi et al. (Diabetologia 50:747–751, 2007) and Hayashi ... Cited by 21 - Related articles - BL Direct - All 3 versions
- ►endojournals.org Y Horikawa, K Miyake, K Yasuda, M Enya, Y … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Results: A total of 15 SNPs were genotyped. Eight SNPs in five loci were found
to be associated with type 2 diabetes: rs3802177 [odds ratio (OR) = 1.16 (95%
confidence interval (CI) 1.05–1.27); P = 4.5 x 10 –3 ] in SLC30A8; ... Cited by 20 - Related articles - All 3 versions
R Rong, RL Hanson, D Ortiz, C Wiedrich, S … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—FTO provided the strongest evidence for replication, where SNPs were
associated with type 2 diabetes (odds ratio = 1.20 per copy of the risk allele,
P = 0.03) and BMI (P = 0.002). None of the other previously reported SNPs ... Cited by 7 - Related articles - All 3 versions
SM Ruchat, CE Elks, RJF Loos, MC Vohl, SJ … - Acta Diabetologica, 2009 - Springer Page 1. ORIGINAL ARTICLE Association between insulin secretion, insulin sensitivity
and type 2 diabetes susceptibility variants identified in genome-wide ... Cited by 5 - Related articles - All 2 versions
H Saadi, N Nagelkerke, SG Carruthers, S … - Diabetes Research and Clinical Practice, 2008 - Elsevier We genotyped the two TCF7L2 single nucleotide polymorphisms (SNPs) rs12255372
and rs7903146 in 368 adult subjects. Homeostatic model assessment (HOMA) was
used to assess beta cell function (HOMA2-%B) and insulin resistance ... Cited by 6 - Related articles - All 14 versions
H Joost - Obesity Facts, 2008 - content.karger.com Type 2 diabetes mellitus is a complex, polygenic disease with a heterogeneous
pathophysiology, mainly characterised by obesity-associated insulin resistance
and a progressive failure of pancreatic -cells. Predominant risk factors ... Cited by 2 - Related articles - All 3 versions
O Alsmadi, K Al-Rubeaan, G Mohamed, F … - BMC Medical Genetics, 2008 - biomedcentral.com For rs7903146, the T allele frequency of the cases (0.415) was not different
from that observed in the controls (0.405). The crude odds ratio (OR) was 1.04
with a 95% CI of 0.86–1.27 (P = 0.675). For rs12255372, the T allele ... Related articles - Cached - All 2 versions
