P Fischer-Posovszky, M Wabitsch, Z Hochberg - Hormone and metabolic …, 2007 - cat.inist.fr Adipose tissue is the body's largest repository of energy and it plays an important role in total
energy homeostasis. Moreover, it is now well recognized as an endocrine organ. A wide range
of different factors including complex proteins as well as fatty acids, prostaglandins, and ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SC Manolagas, M Almeida - Molecular Endocrinology, 2007 - Endocrine Soc The Wnt/ß-catenin signaling pathway affects several biological processes ranging from embryonic
development, patterning, and postembryonic stem cell fate, to bone formation and insulin secretion
in adulthood. ß-Catenin mediates canonical Wnt signaling by binding to and activating ... Cited by 31 - Related articles - All 3 versions
K Maiese, ZZ Chong, YC Shang - Current medicinal chemistry, 2007 - pubmedcentral.nih.gov Diabetes mellitus (DM) is a significant healthcare concern worldwide that affects more than 165
million individuals leading to cardiovascular disease, nephropathy, retinopathy, and widespread
disease of both the peripheral and central nervous systems. The incidence of ... Cited by 27 - Related articles - BL Direct - All 6 versions
- ►nih.gov TC Prestwich, OA MacDougald - Current opinion in cell biology, 2007 - Elsevier Adipocyte differentiation consists of a complex series of events in which scores of cellular and
extracellular factors interact to transform a fibroblast-like preadipocyte into a mature, lipid-filled
adipocyte. Many of the pathways influencing this process have been identified using well- ... Cited by 21 - Related articles - All 4 versions
ZZ Chong, YC Shang, K Maiese - Current neurovascular …, 2007 - pubmedcentral.nih.gov Impacting a significant portion of the world's population with increasing incidence in
minorities, the young, and the physically active, diabetes mellitus (DM) and its complications
affect approximately 20 million individuals in the United States and over 100 million ... Cited by 16 - Related articles - BL Direct - All 3 versions
- ►nih.gov K Maiese, F Li, ZZ Chong, YC Shang - Pharmacology and Therapeutics, 2008 - Elsevier No longer considered to be exclusive to cellular developmental pathways, the Wnt family of secreted
cysteine-rich glycosylated proteins has emerged as versatile targets for a variety of conditions
that involve cardiovascular disease, aging, cancer, diabetes, neurodegeneration, and ... Cited by 12 - Related articles - All 4 versions
- ►nih.gov K Maiese - Biomedicine & Pharmacotherapy, 2008 - Elsevier Oxidative stress is a principal pathway for the dysfunction and ultimate destruction of cells in
the neuronal and vascular systems for several disease entities, not promoting the ravages of
oxidative stress to any less of a degree than diabetes mellitus. Diabetes mellitus is ... Cited by 12 - Related articles - All 3 versions
- ►nih.gov K Maiese, ZZ Chong, F Li, YC Shang - Progress in neurobiology, 2008 - Elsevier Given that erythropoietin (EPO) is no longer believed to have exclusive biological activity in the
hematopoietic system, EPO is now considered to have applicability in a variety of nervous system
disorders that can overlap with vascular disease, metabolic impairments, and immune ... Cited by 11 - Related articles - All 4 versions
AC Carpentier - Diabetes and Metabolism, 2008 - Elsevier Insulin resistance (IR) and impaired glucose-stimulated insulin secretion (GSIS) are the two primary
pathophysiological abnormalities leading to the development of type 2 diabetes (T2D). Over
the past two decades, a large body of work has implicated enhanced delivery of fatty ... Cited by 8 - Related articles - BL Direct - All 2 versions
- ►jbc.org W Guo, J Flanagan, R Jasuja, J Kirkland, L Jiang, S … - Journal of Biological …, 2008 - ASBMB The effects of myostatin on adipogenic differentiation are poorly understood, and the underlying
mechanisms are unknown. We determined the effects of human recombinant myostatin protein
on adipogenesis of bone marrow-derived human mesenchymal stem cells (hMSCs) and ... Cited by 6 - Related articles - All 5 versions