TS Kern - Exp Diabetes Res, 2007 - hindawi.com Diabetes causes metabolic and physiologic abnormalities in the retina, and these
changes suggest a role for inflammation in the development of diabetic
retinopathy. These changes include upregulation of iNOS, COX-2, ICAM-1, ... Cited by 34 - Related articles - View as HTML - All 12 versions
L Zheng, Y Du, C Miller, RA Gubitosi-Klug, TS … - Diabetologia, 2007 - Springer Page 1. ARTICLE Critical role of inducible nitric oxide synthase in degeneration
of retinal capillaries in mice with streptozotocin-induced diabetes ... Cited by 29 - Related articles - BL Direct - All 7 versions
- ►iovs.org L Zheng, B Gong, DA Hatala, TS Kern - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. I/R injury to the retinas was induced in Lewis rats and C57BL/6J mice
by elevating intraocular pressure (IOP), and reperfusion was established
immediately afterward. Some rats were pretreated with aminoguanidine (AMG, ... Cited by 21 - Related articles - BL Direct - All 3 versions
- ►iovs.org M Al-Shabrawey, M Rojas, T Sanders, A … - Investigative Ophthalmology & Visual Science, 2008 - ARVO 1 From the Oral Biology and Anatomy, School of Dentistry, the 2 Vascular Biology
Center, and the 3 Departments of Pharmacology and Toxicology, 6 Internal
Medicine, 7 Ophthalmology, and 8 Cellular Biology and Anatomy, Medical ... Cited by 14 - Related articles - All 4 versions
CS Thompson - Current pharmaceutical design, 2008 - ingentaconnect.com Abstract: The prevalence of diabetes mellitus is increasing worldwide at an
alarming rate due to population growth, obesity, sedentary lifestyle and aging.
Consequently, diabetic microvascular complications (retinopathy and ... Cited by 10 - Related articles - BL Direct - All 3 versions
BA Furlani, CH Meyer, EB Rodrigues, M Maia … - Expert Opin. Emerging Drugs, 2007 - informahealthcare.com Diabetic macular edema (DME) is the most frequent cause of severe vision
impairment in patients with non-proliferative diabetic retinopathy. Even though
patients should achieve optimal glycemic control, normalization of blood ... Cited by 9 - Related articles - BL Direct - All 6 versions
JZ Zhang, X Xi, L Gao, TS Kern - Current Eye Research, 2007 - informahealthcare.com Purpose: This study was conducted to examine the effect of
angiotensin-converting enzyme (ACE) inhibitors on the development of early
stages of diabetic retinopathy. Methods: Rats were made diabetic by ... Cited by 7 - Related articles - BL Direct - All 4 versions
JA Phipps, EP Feener - Kidney International, 2008 - nature.com Diabetic retinopathy and diabetic nephropathy are common microvascular
complications of diabetes. The kallikrein–kinin system (KKS) has been
implicated in the development of both conditions, and, in particular, ... Cited by 6 - Related articles - All 4 versions
TS Kern, AJ Barber - The Journal of Physiology, 2008 - pubmedcentral.nih.gov Diabetic retinopathy has long been recognized as a vascular disease that
develops in most patients, and it was believed that the visual dysfunction that
develops in some diabetics was due to the vascular lesions used to ... Cited by 7 - Related articles - All 7 versions
AP Adamis, AJ Berman - Seminars in Immunopathology, 2008 - Springer Abstract There is an accumulating body of evidence that immunological mechanisms
play a prominent role in the pathogenesis of diabetic retinopathy (DR), which is
charac- terized by many features typical of inflammation. The upregulation ... Cited by 7 - Related articles - BL Direct - All 3 versions
