JA Jefferson, SJ Shankland, RH Pichler - Kidney International, 2008 - nature.com Proteinuria is the hallmark of diabetic kidney disease (DKD) and is an independent risk factor for
both renal disease progression, and cardiovascular disease. Although the characteristic pathological
changes in DKD include thickening ... Cited by 13 - Related articles - All 3 versions
WD Comper, LM Hilliard, DJ Nikolic- … - American Journal of …, 2008 - Am Physiological Soc 125 articles, 43 of which you can access free at: This article cites http://ajprenal.physiology.org/
cgi/content/full/295/6/F1589#BIBL ... 4 other HighWire hosted articles: This article has been cited
by ... [PDF] [Full Text] , March ... Cited by 12 - Related articles - All 3 versions
M Petersen, M Thorikay, M Deckers, M Van Dinther, … - Kidney International, 2007 - nature.com Progressive kidney fibrosis precedes end-stage renal failure in up to a third of patients with
diabetes mellitus. Elevated intra-renal transforming growth factor- (TGF- ) is thought to underlie
disease progression by promoting ... Cited by 11 - Related articles - BL Direct - All 3 versions
CS Thompson - Current pharmaceutical design, 2008 - ingentaconnect.com Abstract: The prevalence of diabetes mellitus is increasing worldwide at an alarming rate due to
population growth, obesity, sedentary lifestyle and aging. Consequently, diabetic microvascular
complications (retinopathy and ... Cited by 10 - Related articles - BL Direct - All 3 versions
Y Shao, M He, L Zhou, T Yao, Y Huang, L Lu - Acta Pharmacologica Sinica, 2008 - nature.com Streptozotocin (STZ) injection-induced diabetic rats were used in the experiment. The animals were
divided into 3 groups: (1) control; (2) STZ-induced diabetes; and (3) STZ-induced diabetes with
chronic Ang (1–7) treatment ... Cited by 6 - Related articles - All 4 versions
DJ Leehey, AK Singh, JP Bast, P Sethupathi, R Singh - Translational Research, 2008 - Elsevier Substantial evidence suggests that the intrarenal renin-angiotensin system (RAS) plays a role in the
pathogenesis of diabetic nephropathy. Although the glomerular RAS is activated in the streptozotocin
(STZ)-diabetic rat, the status of ... Cited by 4 - Related articles - All 13 versions
HS Lee, CY Song - American Journal of Nephrology, 2008 - content.karger.com Glomerulosclerosis frequently complicates most renal diseases and is characterized by mesangial
matrix accumulation. Oxidized low-density lipoprotein (Ox-LDL) could induce oxidative stress and
profibrotic gene expression in ... Cited by 2 - Related articles - All 4 versions
X Ren, G Guan, G Liu, G Liu - Pharmacology, 2008 - content.karger.com Diabetic nephropathy is a major complication of dia- betes mellitus (DM) and an important cause of
morbid- ity and mortality in diabetic patients [1] . To prevent the progression toward chronic renal
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LM Hilliard, LM Russo, WD Comper - Am J Nephrol, 2009 - content.karger.com Background: Recent studies suggest that expression of the transforming growth factor- (TGF-
)-inducible gene-h3 ( ig-h3) and its anti-lysosomal activity may be responsible for the development
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P Balakumar, MK Arora, SS Ganti, J Reddy, M … - Pharmacological Research, 2009 - Elsevier Chronic diabetes mellitus is associated with various complications such as retinopathy, neuropathy,
nephropathy, cardiomyopathy, vasculopathy, dermatopathy and encephalopathy. Nephropathy is one of
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