JM Zabolotny, YB Kim, LA Welsh, EE Kershaw … - Journal of Biological Chemistry, 2008 - ASBMB Protein-tyrosine phosphatase 1B (PTP1B) is a major negative regulator of insulin
and leptin sensitivity. PTP1B overexpression in adipose tissue and skeletal
muscle of humans and rodents may contribute to insulin resistance and ... Cited by 15 - Related articles - All 9 versions
I Nieto-Vazquez, S Fernandez-Veledo, DK … - Archives of Physiology and Biochemistry, 2008 - informahealthcare.com Adipose tissue secretes proteins which may influence insulin sensitivity. Among
them, tumour necrosis factor (TNF)-alpha has been proposed as a link between
obesity and insulin resistance because TNF-alpha is overexpressed in ... Cited by 11 - Related articles - All 5 versions
- ►animal-science.org M Lorenzo, S Fernandez-Veledo, R Vila- … - Journal of animal Science, 2008 - animal-science.org Insulin resistance is an important contributor to the pathogenesis of type 2
diabetes, and obesity is a risk factor for its development, in part because
adipose tissue secretes proteins, called adipokines, that may influence ... Cited by 8 - Related articles - All 5 versions
- ►diabetesjournals.org I Nieto-Vazquez, S Fernández-Veledo, C de … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—IL-6 per se increased glucose uptake by activating serine/threonine
protein kinase 11 (LKB1)/AMP-activated protein kinase/protein kinase B substrate
of 160 kDa (AS160) pathway. A dual effect on insulin action was observed ... Cited by 8 - Related articles - All 5 versions
- ►endojournals.org S Fernandez-Veledo, I Nieto-Vazquez, J de … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Results: Adipocytes differentiated for 14 d gain insulin sensitivity on glucose
uptake and inhibition of lipolysis, but prolonged cultures develop an
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- ►endojournals.org S Aga-Mizrachi, T Brutman-Barazani, AI … - Endocrinology, 2008 - Endocrine Soc Whereas positive regulatory events triggered by insulin binding to insulin
receptor (IR) have been well documented, the mechanism by which the activated IR
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- ►endocrinology-journals.org MR Martins, AKG Vieira, EPG de Souza, AS … - Journal of Endocrinology, 2008 - Soc Endocrinology Human overnutrition has caused a rise in the prevalence of obesity in recent
years. In addition to the deleterious effects of obesity during childhood,
long-term effects in adulthood have been described as well. For instance, ... Cited by 1 - Related articles - All 4 versions
JF Ndisang… - Endocrinology, 2009 - Endocrine Soc Emerging evidence indicates that aldosterone causes oxidative stress by
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S Fernandez-Veledo, I Nieto-Vazquez, R … - Archives of Physiology and Biochemistry, 2009 - ingentaconnect.com Insulin resistance is an important contributor to the pathogenesis of type 2
diabetes (T2D) and obesity is a risk factor for its development. In the obese
state an altered secretion pattern, with increase in pro- inflammatory and ... Related articles - All 4 versions
