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Scholar Results 1 - 10 of 12 citing Lehman: P2 Promoter variants of the hepatocyte nuclear factor 4α gene are associated with.... (0.12 sec) 

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson …

- diabetesjournals.org
I Barroso, J Luan, E Wheeler, P Whittaker, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Single nucleotide polymorphisms (SNPs) in the P2 promoter region of
HNF4A were originally shown to be associated with predisposition for type 2
diabetes in Finnish, Ashkenazi, and, more recently, Scandinavian ...
Cited by 7 - Related articles - All 8 versions

HNF4A genetic variants: role in diabetes


L Love-Gregory, MA Permutt - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com
Purpose of review: Variants in the hepatocyte nuclear factor 4α (HNF4A) gene
play a role in the development of diabetes mellitus. Although genetic variation
in and around HNF4A regulatory regions has received considerable attention, ...
Cited by 6 - Related articles - BL Direct - All 5 versions

FitSNPs: highly differentially expressed genes are more likely to have variants associated …


R Chen, A Morgan, J Dudley, T Deshpande, L … - Genome Biology, 2008 - dx.doi.org
We analyzed all human microarray studies from the Gene Expression Omnibus, and
calculated the observed frequency of differential expression, which we called
differential expression ratio, for every human gene. Analysis conducted in ...
Cited by 3

Studies in 3,523 Norwegians and Meta-Analysis in 11,571 Subjects Indicate That Variants …


S Johansson, H Ræder, SÅ Eide, K Midthjell, … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE— Recent publications have found an association between common
variants near the hepatocyte nuclear factor 4α (HNF4A) P2 promoter and type 2
diabetes in some populations but not in others, and the role for HNF4A in ...
Cited by 1 - Related articles - BL Direct - All 3 versions

Studies in 3,523 Norwegians and Meta-Analysis in 11,571 Subjects Indicate That Variants …


S Johansson, H Ræder, SÅ Eide, K Midthjell, … - DIABETES, 2007 - Am Diabetes Assoc
Page 1. Studies in 3,523 Norwegians and Meta-Analysis in 11,571 Subjects
Indicate That Variants in the Hepatocyte Nuclear Factor ...
Related articles

Pathomechanisms of Type 2 Diabetes Genes

- spendocrinologia.org.pe [PDF] 
H Staiger, F Machicao, A Fritsche, HU Haring - Endocrine Reviews, 2009 - Endocrine Soc
Type 2 diabetes mellitus is a complex metabolic disease that is caused by
insulin resistance and β-cell dysfunction. Furthermore, type 2 diabetes has an
evident genetic component and represents a polygenic disease. During the ...
Related articles - All 4 versions

Studies in 3,523 Norwegians (HUNT2) and Meta-Analysis in 11,571 Subjects Indicate that …

- diabetesjournals.org [PDF] 
S Johansson, H Ræder, SÅ Eide, K Midthjell, … - Diabetes, 2007 - Am Diabetes Assoc
Page 1. Studies in 3,523 Norwegians (HUNT2) and Meta-Analysis in 11,571
Subjects Indicate that Variants in the HNF4A P2 Region are ...
Related articles - All 2 versions

Population-specific risk of type 2 diabetes (T2D) conferred by HNF4A P2 promoter variants: a …


M Delgado, RJ Neuman, J Zhao, R Sherva, B … - Diabetes - Am Diabetes Assoc
Page 1. Population-specific risk of type 2 diabetes (T2D) conferred by HNF4A
P2 promoter variants: a lesson for replication studies ...

Down-Regulation of Hepatic HNF4 {alpha} Gene Expression during Hyperinsulinemia via …


X Xie, H Liao, H Dang, W Pang, Y Guan, X … - Molecular Endocrinology, 2009 - Endocrine Soc
Mutations in the coding region of hepatocyte nuclear factor 4 (HNF4 ), and its
upstream promoter (P2) that drives expression in the pancreas, are known to lead
to maturity-onset diabetes of the young 1 (MODY1). HNF4 also controls ...
Related articles - All 4 versions

[PDF] A Lesson for Replication Studies


E Zeggini, MN Weedon, S Hunt, R Venkatesh, … - Diabetes, 2008 - Am Diabetes Assoc
Inês Barroso,1 Jian'an Luan,2 Eleanor Wheeler,1 Pamela Whittaker,1 Jon Wasson,3
Eleftheria Zeggini,4,5 Michael N. Weedon,6 Sarah Hunt,1 Ranganath Venkatesh,1
Timothy M. Frayling,6 Marcos Delgado,1,4 Rosalind J. Neuman,3 Jinghua ...


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