P Monti, M Scirpoli, P Maffi, N Ghidoli, F … - The Journal of …, 2008 - pubmedcentral.nih.gov Successful transplantation requires the prevention of allograft rejection and, in the case of transplantation
to treat autoimmune disease, the suppression of autoimmune responses. The standard immunosuppressive
treatment regimen given to patients with autoimmune type 1 diabetes who have received ... Cited by 28 - Related articles - BL Direct - All 7 versions
A Riboulet-Chavey, F Diraison, LK Siew, FS Wong, GA … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Clonal MIN6 β-cells or CD1 mouse pancreatic islets
were infected with recombinant adenoviruses encoding enhanced green fluorescent protein
(eGFP/null), constitutively active AMPK (AMPK-CA), or dominant-negative AMPK ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org E Martinuzzi, G Novelli, M Scotto, P Blancou, JM Bach, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—CD8 + T-cell reactivities were less frequent at follow-up, as 28.6% of responses
tested positive at type 1 diabetes diagnosis vs. 13.2% after a median of 11 months (P =
0.003). While GAD and IA-2 autoantibody (aAb) titers were unchanged in 75% of cases, ... Cited by 12 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org I Jarchum, JC Baker, T Yamada, T Takaki, MP Marron, … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—We found that HLA-A*0201-restricted T-cells isolated from the islets of the transgenic
mice were specific for Ins1 L3–11, Ins1 B5–14, and Ins1/2 A2–10. Insulin-reactive T-cells were
present in the islets of mice as young as 5 weeks of age, suggesting an important function ... Cited by 10 - Related articles - BL Direct - All 4 versions
A Skowera, RJ Ellis, R Varela-Calviño, S … - The Journal of …, 2008 - pubmedcentral.nih.gov Ania Skowera,1,2 Richard J. Ellis,1 Ruben Varela-Calviño,3 Sefina Arif,1 Guo Cai Huang,4 Cassie
Van-Krinks,1 Anna Zaremba,1 Chloe Rackham,1 Jennifer S. Allen,1 Timothy IM Tree,1 Min
Zhao,4 Colin M. Dayan,5 Andrew K. Sewell,6 Wendy Unger,7 Jan W. Drijfhout,7 Ferry ... Cited by 9 - Related articles - All 11 versions
- ►nih.gov I Jarchum, L Nichol, M Trucco, P Santamaria, TP … - Clinical Immunology, 2008 - Elsevier CD8 + T cells play an important role in the development of type 1 diabetes (T1D) in NOD mice
and humans. IGRP (islet-specific glucose-6-phosphatase catalytic subunit-related protein) has
emerged in recent years as a major antigen in NOD mice. Therefore, we aimed to ... Cited by 7 - Related articles - All 3 versions
- ►nih.gov KL Graham, N Sanders, Y Tan, J Allison, TWH Kay … - Journal of …, 2008 - Am Soc Microbiol Infection modulates type 1 diabetes, a common autoimmune disease characterized by the destruction
of insulin-producing islet β cells in the pancreas. Childhood rotavirus infections have been associated
with exacerbations in islet autoimmunity. Nonobese diabetic (NOD) mice develop ... Cited by 6 - Related articles - All 8 versions
C Baker, LG Petrich de Marquesini, AJ Bishop, AJ … - Journal of Clinical …, 2008 - Springer Abstract Purpose In this study, we explored the breadth of CD8 T cell reactivity to preproinsulin
(PPI) in type 1 diabetes. Materials and Methods We tested a complete peptide set in pools covering
all 406 potential 8–11mer epitopes of PPI and 61 algorithm-predicted human leukocyte ... Cited by 6 - Related articles - All 2 versions
- ►diabetesjournals.org BO Roep - Diabetes, 2008 - Am Diabetes Assoc While differentiating T-cell autoreactivity against pancreatic islets between type 1 diabetic patients
and nondiabetic control subjects has, over time, proven to be a difficult task, the ultimate challenge
for cellular markers of this disease will involve the definition of immunological measures ... Cited by 5 - Related articles - BL Direct - All 3 versions
R Mallone, P van Endert - Current Diabetes Reports, 2008 - Springer T lymphocytes' crucial role in the autoimmune process leading to insulin-dependent type 1 diabetes
is now universally recognized. Research focuses on identifying pathogenic and nonpathogenic
T cells, understanding how they are primed and expanded, characterizing their antigen ... Cited by 3 - Related articles - BL Direct - All 4 versions
