D Westermann, S Van Linthout, S Dhayat, N Dhayat … - Basic research in …, 2007 - Springer D.Westermann · S.Van Linthout · S. Dhayat · N. Dhayat · M. Noutsias · F. Spillmann · A. Riad ·
H.-P. Schultheiss · C. Tschöpe, MD ( ) Dept. of Cardiology and Pneumonology Charité – Universitätsmedizin
Berlin Campus Benjamin Franklin Hindenburgdamm 30 12200 Berlin, Germany Tel.: ... Cited by 21 - Related articles - BL Direct - All 5 versions
K Defea - British Journal of Pharmacology, 2008 - pubmedcentral.nih.gov G-protein-coupled receptors (GPCRs), also known as seven transmembrane receptors
(7-TMRs), are the largest protein receptor superfamily in the body. These receptors and their
ligands direct a diverse array of physiological responses, and hence have broad ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org D Westermann, S Van Linthout, S Dhayat, N Dhayat, F … - Diabetes, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Diabetes was induced in 24 Sprague-Dawley rats by
injection of streptozotozin (STZ) (70 mg/kg). Diabetic animals were treated with the interleukin
converting enzyme (ICE) inhibitor (ICEI) (n = 12) or with a placebo (n = 12). Nondiabetic ... Cited by 14 - Related articles - BL Direct - All 7 versions
CS Thompson - Current pharmaceutical design, 2008 - ingentaconnect.com Abstract: The prevalence of diabetes mellitus is increasing worldwide at an alarming rate due
to population growth, obesity, sedentary lifestyle and aging. Consequently, diabetic microvascular
complications (retinopathy and nephropathy) and macrovascular complications (coronary ... Cited by 10 - Related articles - BL Direct - All 3 versions
D Westermann, HP Schultheiss, C Tschöpe - International …, 2008 - Elsevier An intensification of the local cardiac kallikrein–kinin system (KKS) is thought to delay the development
of cardiac failure. Since myocardial infarction is one of the leading causes of death in the developed
countries, the role of the kallikrein–kinin system was studied in numerous experimental ... Cited by 12 - Related articles - All 2 versions
- ►jimmunol.org A Riad, S Jager, M Sobirey, F Escher, A … - The Journal of …, 2008 - Am Assoc Immnol Left ventricular (LV) remodeling is known to contribute to morbidity and mortality after myocardial
infarction (MI). Because LV remodeling is strongly associated with an inflammatory
response, we investigated whether or not TLR-4 influences LV remodeling and survival in ... Cited by 9 - Related articles - All 4 versions
CR Ban, SM Twigg - Vascular Health and Risk Management, 2008 - pubmedcentral.nih.gov Diabetes mellitus is characterized by a lack of insulin causing elevated blood glucose, often
with associated insulin resistance. Over time, especially in genetically susceptible
individuals, such chronic hyperglycemia can cause tissue injury. One pathological ... Cited by 7 - Related articles - All 8 versions
S Van Linthout, U Seeland, A Riad, O Eckhardt, M … - Basic Research in …, 2008 - Springer Several studies have shown that dysregulation in the degradation of the extracellular matrix
(ECM) by ma- trix metalloproteinases (MMPs), specifically MMP-2 and MMP-9, is involved in
the pathogenesis of a wide spectrum of cardiovascular disorders, including ath- Cited by 8 - Related articles - All 3 versions
D Westermann, A Riad, O Lettau, A Roks, K Savvatis, … - Hypertension, 2008 - Am Heart Assoc Pharmacological renin inhibition with aliskiren is an effective antihypertensive drug
treatment, but it is currently unknown whether aliskiren is able to attenuate cardiac failure independent
of its blood pressure–lowering effects. We investigated the effect of aliskiren on cardiac ... Cited by 10 - Related articles - All 5 versions
Y Shi, C Chen, U Lisewski, U Wrackmeyer, M … - Journal of the American …, 2009 - Elsevier CAR is involved in virus uptake into various cell types. It has therefore been suggested as a therapeutic
target to prevent or treat Coxsackievirus B3 (CVB3)-induced diseases such as myocarditis and
cardiomyopathy. Recent work in CAR-deficient animals has indicated a role in embryonic ... Cited by 6 - Related articles - All 22 versions
