- ►endojournals.org SY Goh, ME Cooper - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Evidence Synthesis: In this review we report on how these AGEs may exert
deleterious effects in diabetes, as well as address current strategies to
interrupt the formation or action of AGEs. First, AGEs act directly to ... Cited by 42 - Related articles - BL Direct - All 4 versions
S Rahbar - Cell biochemistry and biophysics, 2007 - Springer Abstract Accelerated formation of advanced glycation/ lipoxidation and
endproducts (AGEs/ALEs) has been implicated in the pathogenesis of various
diabetic com- plications. Several natural and synthetic compounds have been ... Cited by 10 - Related articles - BL Direct - All 5 versions
- ►nih.gov CA Gleissner, E Galkina, JL Nadler, K Ley - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier Diabetes mellitus is one of the major risk factors for atherosclerosis, an
inflammatory disease of the arterial wall, in which leukocytes and oxidized
lipoproteins accumulate leading to formation of fatty streaks and ... Cited by 7 - Related articles - All 3 versions
- ►oxfordjournals.org V Besson, V Brault, A Duchon, D Togbe, JC … - Human Molecular Genetics, 2007 - Oxford Univ Press Monosomy 21 is a rare human disease due to gene dosage errors disturbing a
variety of physiological and morphological systems including brain, skeletal,
immune and respiratory functions. Most of the human condition corresponds ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org G Spinetti, N Kraenkel, C Emanueli, P … - Cardiovascular Research, 2008 - cardiovascres.oxfordjournals.org Over the past two decades, extensive research has focused on arterial
remodelling in both physiological and pathological ageing. The concept now
describes the growth as well as the rearrangement of cellular components ... Cited by 6 - Related articles - All 4 versions
JL Figarola, S Loera, Y Weng, N Shanmugam, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Previous studies have shown that LR-90, a new inhibitor
of AGE formation, prevented the develop- ment of experimental type 1 diabetic
nephropathy. In this study, we examined the effects of LR-90 in the Zucker ... Cited by 5 - Related articles - BL Direct - All 3 versions
- ►physiology.org A Csiszar, Z Ungvari - American Journal of Physiology- Heart and Circulatory …, 2008 - Am Physiological Soc In their article, Gao et al. (13) tested the hypothesis that impaired nitric
oxide-dependent dilation in small coronary arteries in Type 2 diabetes results,
in part, from elevated production of superoxide induced by the interaction ... Cited by 5 - Related articles - All 4 versions
KC Sourris, JM Forbes - Current Drug Targets, 2009 - ingentaconnect.com Abstract: Diabetes, is a metabolic disorder characterised by chronic
hyperglycaemia, hypertension, dyslipidaemia, micro- albuminuria and
inflammation. Moreover, there are a number of complications associated with ... Cited by 3 - Related articles - All 2 versions
- ►diabetesjournals.org N Shanmugam, JL Figarola, Y Li, PM … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Synthetic ALE (malondialdehyde-lysine [MDA-Lys]) (50 μmol/l) could
induce oxidant stress and also activate the transcriptional factor nuclear
factor-κB (NF-κB) in THP-1 monocytes. MDA-Lys also significantly ... Cited by 3 - Related articles - BL Direct - All 4 versions
