PC Butler, JJ Meier, AE Butler, A Bhushan - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov Replication of beta cells is an important source of beta-cell expansion in early
childhood. The recent linkage of type 2 diabetes with several transcription
factors involved in cell cycle regulation implies that growth of the ... Cited by 41 - Related articles - BL Direct - All 3 versions
- ►alphamedpress.org B Davani, L Ikonomou, BM Raaka, E Geras- … - Stem Cells, 2007 - AlphaMed Press Islet transplantation offers improved glucose homeostasis in diabetic patients,
but transplantation of islets is limited by the supply of donor pancreases.
Undifferentiated precursors hold promise for cell therapy because they can ... Cited by 29 - Related articles - BL Direct - All 5 versions
S Efrat - Advanced drug delivery reviews, 2008 - Elsevier Beta-cell replacement is considered the optimal treatment for type 1 diabetes,
however, it is hindered by a shortage of human organ donors. Given the
difficulty of expanding adult beta cells in vitro, stem/progenitor cells, ... Cited by 12 - Related articles - All 4 versions
R Gallo, F Gambelli, B Gava, F Sasdelli, V … - Cell Death & Differentiation, 2007 - nature.com Cellular models and culture conditions for in vitro expansion of
insulin-producing cells represent a key element to develop cell therapy for
diabetes. Initial evidence that human -cells could be expanded after ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►alphamedpress.org CA Fraker, S Alvarez, P Papadopoulos, J … - Stem Cells, 2007 - AlphaMed Press Despite progress in our knowledge about pancreatic islet specification, most
attempts at differentiating stem/progenitor cells into functional,
transplantable β cells have met only with moderate success thus far. A ... Cited by 11 - Related articles - BL Direct - All 6 versions
L Baeyens, L Bouwens - Diabetes Obes Metab, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 6 - Related articles - All 3 versions
L Ikonomou, E Geras-Raaka, BM Raaka, MC … - Cell proliferation, 2008 - pubmedcentral.nih.gov Previously, we characterized human islet-derived precursor cells (hIPCs) as
mesenchymal stem cells that migrate out from islets in vitro and can
differentiate into functional islet-like structures following proliferative ... Cited by 2 - Related articles - BL Direct - All 5 versions
S Efrat - The Review of Diabetic Studies: RDS, 2008 - pubmedcentral.nih.gov Ex-vivo generation of human insulin-producing cells is considered a promising
approach to providing an abundant source of cells for beta-cell replacement
therapy in diabetes. Expansion of adult beta-cells from the limited number ... Cited by 1 - Related articles - All 3 versions
