WS Simonides, MA Mulcahey, EM Redout, … - The Journal of …, 2008 - pubmedcentral.nih.gov Thyroid hormone is a critical determinant of cellular metabolism and differentiation. Precise
tissue-specific regulation of the active ligand 3,5,3′-triiodothyronine (T3) is achieved by the
sequential removal of iodine groups from the thyroid hormone molecule, with type 3 ... Cited by 23 - Related articles - BL Direct - All 9 versions
- ►koki.hu [PDF] B Gereben, AM Zavacki, S Ribich, BW Kim, SA … - Endocrine …, 2008 - Endocrine Soc The iodothyronine deiodinases initiate or terminate thyroid hormone action and therefore are
critical for the biological effects mediated by thyroid hormone. Over the years, research has focused
on their role in preserving serum levels of the biologically active molecule T 3 during ... Cited by 22 - Related articles - All 5 versions
- ►aspetjournals.org KA Rasbach, RG Schnellmann - Journal of Pharmacology and Experimental …, 2008 - ASPET Mitochondrial damage is often both the cause and outcome of cell injury resulting from a variety
of toxic insults, hypoxia, or trauma. Increasing mitochondrial biogenesis after renal proximal tubular
cell (RPTC) injury accelerated the recovery of mitochondrial and cellular functions ... Cited by 16 - Related articles - All 3 versions
- ►nih.gov GD Sagar, B Gereben, I Callebaut, JP Mornon … - Molecular and Cellular …, 2007 - Am Soc Microbiol Ubiquitination is a critical posttranslational regulator of protein stability and/or subcellular
localization. Here we show that ubiquitination can also regulate proteins by transiently inactivating
enzymatic function through conformational change in a dimeric enzyme, which can be ... Cited by 11 - Related articles - BL Direct - All 9 versions
S Costford, A Gowing, ME Harper - Current Opinion in Clinical …, 2007 - journals.lww.com Purpose of review Obesity is associated with many health problems and its prevalence is rapidly
increasing worldwide. Very few pharmaceutical compounds are available for obesity
treatment. Strategies for the development of compounds can be targeted to the outcomes ... Cited by 7 - Related articles - BL Direct - All 2 versions
LK Stewart, JL Soileau, D Ribnicky, ZQ … - Metabolism: clinical …, 2008 - pubmedcentral.nih.gov Quercetin, a polyphenolic compound and a major bioflavonoid in the human diet, has anti-inflammatory
properties and has been postulated to enhance energy expenditure (EE). We sought to determine
whether quercetin alters body weight, body composition, EE, and circulating markers of ... Cited by 7 - Related articles - All 5 versions
R Grozovsky, S Ribich, ML Rosene, MA Mulcahey, SA … - Endocrinology, 2009 - Endocrine Soc The thyroid hormone activating type 2 deiodinase (D2) is known to play a role in brown adipose
tissue-mediated adaptive thermogenesis in rodents, but the finding of D2 in skeletal muscle raises
the possibility of a broader metabolic role. In the current study, we examined the ... Cited by 6 - Related articles - All 4 versions
DL St Germain, VA Galton, A Hernandez - Endocrinology, 2009 - Endocrine Soc As is typical of other hormone systems, the actions of the thyroid hormones (TH) differ from tissue
to tissue depending upon a number of variables. In addition to varying expression levels of TH
receptors and transporters, differing patterns of TH metabolism provide a critical ... Cited by 8 - Related articles - All 4 versions
CM Rommens, CM Richael, H Yan, DA … - Plant Biotechnology …, 2008 - interscience.wiley.com Flavonols and caffeoylquinates represent important groups of phenolic antioxidants with
health-promoting activities. The genetic potential of potato (Solanum tuberosum) to produce
high levels of these dietary compounds has not been realized in currently available ... Cited by 2 - Related articles - All 3 versions
AC Bianco - Thyroid, 2008 - liebertonline.com M any attempts have been made to use thyroid hor- mones as therapeutic agents for obesity
and hyper- lipidemia, two syndromes perceived to reflect disordered metabolism. These efforts
were based on observations that thyroid hormones are the most potent thermogenic ... Cited by 1 - Related articles - BL Direct - All 3 versions
