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Scholar Results 1 - 3 of 3 citing Martinic: Minimal Impact of a De Novo–Expressed β-Cell Autoantigen on Spontaneous Diabetes.... (0.08 sec) 

Immunoregulatory mechanisms triggered by viral infections protect from type 1 …


CM Filippi, EA Estes, JE Oldham, MG … - The Journal of Clinical …, 2009 - pubmedcentral.nih.gov
Type 1 diabetes (T1D) is an autoimmune disease that is caused by the destruction of
insulin-producing β cells. Viral infections induce immune responses that can damage β cells
and promote T1D or on the other hand prevent the development of the disease. However, ...
Cited by 1 - Related articles - All 7 versions

Good and bad sides of viruses in Type 1 diabetes


CM Filippi, MG von Herrath - Future Virol., 2009 - Future Medicine
Type 1 diabetes (T1D) is a genetic autoimmune disease that results from the destruction of
insulin-producing β cells in the pancreas [1]. The disease is caused by autoreactive T cells that
infiltrate the pancreatic islets of Langerhans, where they attack and destroy β cells. ...
Related articles - All 3 versions

Genetic-induced Variations in the GAD65 T-cell Repertoire Governs Efficacy of Anti …


D Bresson, M Fradkin, Y Manenkova, D Rottembourg, … - Molecular Therapy, 2009 - nature.com
To enhance efficacy of forthcoming type 1 diabetes (T1D) clinical trials, combination therapies
(CTs) are envisaged. In this study, we showed that efficacy of a CT, using anti-CD3 antibody
and glutamic acid decarboxylase of 65 kd (GAD65)-expressing plasmid, to reverse new- ...
Related articles - All 3 versions


 


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