E Charpantier, J Cancela, P Meda - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Pancreatic beta cells are connected by gap junction channels made
of connexin 36 (Cx36), which permit intercellular exchanges of current-carrying ions (ionic
coupling) and other molecules (metabolic coupling). Previ- ous studies have suggested ... Cited by 10 - Related articles - BL Direct - All 2 versions
- ►rupress.org T Rose, S Efendic, M Rupnik - Journal of General Physiology, 2007 - jgp.rupress.org The Goto Kakizaki (GK) rat is a widely used animal model to study defective glucose-stimulated
insulin release in type-2 diabetes (T2D). As in T2D patients, the expression of several proteins
involved in Ca 2+ -dependent exocytosis of insulin-containing large dense-core vesicles ... Cited by 10 - Related articles - BL Direct - All 5 versions
S Bavamian, P Klee, A Britan, C Populaire, D … - Diabetes Obes …, 2007 - interscience.wiley.com The emergence of pancreatic islets has necessitated the development of a signalling system
for the intra- and inter-islet coordination of β cells. With evolution, this system has evolved into
a complex regulatory network of partially cross-talking pathways, whereby individual cells ... Cited by 6 - Related articles - All 2 versions
K Wellershaus, J Degen, J Deuchars, M Theis, A … - Experimental Cell …, 2008 - Elsevier Connexin36 (Cx36) is the main connexin isoform expressed in neurons of the central nervous
system (CNS) and in pancreatic β-cells, ie two types of excitable cells that share – in spite of
their different origins – a number of common features. Previous studies on Cx36 deficient ... Cited by 3 - Related articles - All 2 versions
- ►endojournals.org F Jaques, H Jousset, A Tomas, AL Prost, CB Wollheim, … - Endocrinology, 2008 - Endocrine Soc Cell-to-cell interactions play an important role in insulin secretion. Compared with intact
islets, dispersed pancreatic β-cells show increased basal and decreased glucose-stimulated
insulin secretion. In this study, we used mouse MIN6B1 cells to investigate the ... Cited by 3 - Related articles - BL Direct - All 3 versions
V Serre-Beinier, D Bosco, L Zulianello, A … - Human Molecular …, 2009 - Oxford Univ Press Previous studies have documented that the insulin-producing β-cells of laboratory rodents are
coupled by gap junction channels made solely of the connexin36 (Cx36) protein, and have shown
that loss of this protein desynchronizes β-cells, leading to secretory defects reminiscent of ... Cited by 2 - Related articles - All 3 versions
F Allagnat, F Alonso, D Martin, A Abderrahmani, G … - Journal of Biological …, 2008 - ASBMB Channels formed by the gap junction protein connexin36 (Cx36) contribute to the proper control
of insulin secretion. We investigated the impact of chronic hyperlipidemia on Cx36 expression
in pancreatic β-cells. Prolonged exposure to the saturated free fatty acid palmitate ... Cited by 2 - Related articles - All 3 versions
E Scemes, S Bavamian, A Charollais, DC … - Cell communication …, 2008 - pubmedcentral.nih.gov Connexins and pannexins have been implicated in the formation of “hemichannels,” which may
account for the uptake and release of membrane-impermeant molecules in single cells. The
in vivo existence of “hemichannels” and their protein composition is still debated. ... Cited by 2 - Related articles - All 6 versions
P Klee, S Bavamian, A Charollais, D Caille, J … - Pancreatic Beta Cell in …, 2007 - Springer Summary. About 30 years ago, pancreatic beta cells were shown to be con- nected by gap junctions
and to exhibit glucose-induced oscillatory electrical activity, two features that were hypothetically
linked to insulin secretion. Since then, gap junctions have been shown to be an obligatory ... Related articles - All 2 versions
T Rose, S Efendic, M Rupnik - The Journal of General Physiology, 2007 - ukpmc.ac.uk The Goto Kakizaki (GK) rat is a widely used animal model to study defective glucose-stimulated
insulin release in type-2 diabetes (T2D). As in T2D patients, the expression of several proteins
involved in Ca 2+ -dependent exocytosis of insulin-containing large dense-core vesicles ... Related articles