AV Gyulkhandanyan, H Lu, SC Lee, A … - Journal of Biological Chemistry, 2008 - ASBMB During insulin secretion, pancreatic α-cells are exposed to Zn 2+ released from
insulin-containing secretory granules. Although maintenance of Zn 2+ homeostasis
is critical for cell survival and glucagon secretion, very little is known ... Cited by 13 - Related articles - All 4 versions
- ►endocrinology-journals.org I Quesada, E Tuduri, C Ripoll, A Nadal - Journal of Endocrinology, 2008 - Soc Endocrinology The secretion of glucagon by pancreatic -cells plays a critical role in the
regulation of glycaemia. This hormone counteracts hypoglycaemia and opposes
insulin actions by stimulating hepatic glucose synthesis and mobilization, ... Cited by 8 - Related articles - All 3 versions
- ►physiology.org P Bansal, Q Wang - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Glucose homeostasis is regulated primarily by the opposing actions of insulin
and glucagon, hormones that are secreted by pancreatic islets from β-cells and
-cells, respectively. Insulin secretion is increased in response to ... Cited by 6 - Related articles - All 3 versions
- ►cell.com P Rorsman, SA Salehi, F Abdulkader, M … - Trends in Endocrinology & Metabolism, 2008 - Elsevier Glucagon, secreted by the α-cells of the pancreatic islets, is the most
important glucose-increasing hormone of the body. The precise regulation of
glucagon release remains incompletely defined but has been proposed to ... Cited by 4 - Related articles - All 5 versions
R Burcelin, C Knauf, PD Cani - Diabetes and Metabolism, 2008 - Elsevier A major, yet poorly understood, feature of type 2 diabetes is the excessive
hepatic glucose production and the corresponding insulin resistance leading to
fasting hyperglycaemia. The tremendous amount of work done to provide the ... Cited by 4 - Related articles - All 2 versions
L Storjohann, B Holst, TW Schwartz - FEBS letters, 2008 - ncbi.nlm.nih.gov Ala substitution of potential metal-ion binding residues in the main
ligand-binding pocket of the Zn2+-activated G protein-coupled receptor 39
(GPR39) receptor did not decrease Zn2+ potency. In contrast, Zn2+ ... Cited by 2 - Related articles - All 8 versions
- ►diabetesjournals.org N Quoix, R Cheng-Xue, L Mattart, Z Zeinoun, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—In 0.5 mmol/l glucose, [Ca 2+ ] c oscillated in some -cells and was
basal in the others. Increasing glucose to 15 mmol/l decreased [Ca 2+ ] c by 30%
in oscillating cells and was ineffective in the others. -Cell I KATP was ... Cited by 1 - Related articles - All 3 versions
- ►physiology.org LS Farhy, Z Du, Q Zeng, PP Veldhuis, ML … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Glucagon counterregulation (GCR) is a key protection against hypoglycemia that
is compromised in diabetes via an unknown mechanism. To test the hypothesis that
-cell-inhibiting signals that are switched off during hypoglycemia amplify ... Cited by 1 - Related articles - All 5 versions
S Bohman, AJF King - Biochemical and Biophysical Research …, 2008 - Elsevier Islet transplantation can reverse hyperglycaemia in Type 1 diabetes patients.
One problem in islet transplantation is a loss of beta cell mass as well as
blunted glucagon responses from the grafted islets. It has been suggested ... Cited by 1 - Related articles - All 3 versions
AOF PULSATILE, G COUNTERREGULATION, … - mljohnson.pharm.virginia.edu 1Departments of Medicine, 2Pharmacology, 3Surgery, and the 4Center for
Biomathematical Technology, University of Virginia, Charlottesville, Virginia. ... Corresponding Author Leon S. Farhy Box 801735 University of Virginia ... Related articles - View as HTML - All 2 versions
