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Scholar Results 1 - 10 of about 33 citing Flowers: Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but.... (0.11 sec) 

Nutrition-induced ketosis alters metabolic and signaling gene networks in liver of …

- physiology.org [PDF] 
JJ Loor, RE Everts, M Bionaz, HM Dann, DE … - Physiological …, 2007 - Am Physiological Soc
Page 1. 1 Running head: Ketosis and bovine hepatic gene networks 1 Nutrition-induced ketosis
alters metabolic and signaling 2 gene networks in liver of periparturient dairy cows § 3 4 Juan
J. Loor 1 *† , Robin E. Everts 1 † , Massimo Bionaz 1 , Heather M. Dann 1 ‡ , Dawn E. 5 ...
Cited by 18 - Related articles - BL Direct - All 4 versions

Fatty acid desaturases in human adipose tissue: relationships between gene …


P Sjögren, J Sierra-Johnson, K Gertow, M Rosell, B … - Diabetologia, 2008 - Springer
Page 1. ARTICLE Fatty acid desaturases in human adipose tissue: relationships between gene
expression, desaturation indexes and insulin resistance P. Sjögren & J. Sierra-Johnson & K.
Gertow & M. Rosell & B. Vessby & U. de Faire & A. Hamsten & M.-L. Hellenius & ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Glycerolipid metabolism and signaling in health and disease

- endojournals.org
M Prentki, SR Madiraju - Endocrine reviews, 2008 - Endocrine Soc
GL/FFA cycle is referred to as a "futile" cycle because it involves continuous formation and hydrolysis
of GL with the release of heat, at the expense of ATP. However, we present evidence underscoring
the "vital" cellular signaling roles of the GL/FFA cycle for many biological processes. ...
Cited by 14 - Related articles - All 5 versions

Skeletal muscle–specific deletion of lipoprotein lipase enhances insulin signaling …


H Wang, LA Knaub, DR Jensen, D Young Jung, EG … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—Nine-week-old SMLPL −/− mice showed no differences in body weight, fat
mass, or whole-body insulin sensitivity, but older SMLPL −/− mice had greater weight gain and
whole-body insulin resistance. High-fat diet feeding accelerated the development of ...
Cited by 13 - Related articles - All 5 versions

Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic …

- jlr.org
MLE MacDonald, RR Singaraja, N Bissada, P … - The Journal of Lipid …, 2008 - ASBMB
A combination of the interrelated metabolic risk factors obesity, insulin resistance,
dyslipidemia, and hypertension, often described as the "metabolic syndrome," is known to increase
the risk of developing cardiovascular disease and diabetes. Stearoyl-coenzyme A ...
Cited by 13 - Related articles - All 6 versions

Cholesterol in islet dysfunction and type 2 diabetes


LR Brunham, JK Kruit, CB Verchere, MR … - The Journal of Clinical …, 2008 - pubmedcentral.nih.gov
Type 2 diabetes (T2D) frequently occurs in the context of abnormalities of plasma
lipoproteins. However, a role for elevated levels of plasma cholesterol in the pathogenesis of
this disease is not well established. Recent evidence suggests that alterations of plasma ...
Cited by 11 - Related articles - BL Direct - All 6 versions

Liver gene expression analysis reveals endoplasmic reticulum stress and …

- physiology.org [PDF] 
MT Flowers, MP Keller, YJ Choi, H Lan, CM … - Physiological …, 2008 - Am Physiological Soc
Page 1. 1 Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic
dysfunction in SCD1-deficient mice fed a very low-fat diet. Matthew T. Flowers 1,2,* , Mark P.
Keller 1 , YounJeong Choi 3 , Hong Lan 1 , Christina Kendziorski 3 , ...
Cited by 10 - Related articles - All 7 versions

Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role …


ZZ Li, M Berk, TM McIntyre, AE Feldstein - Journal of Biological Chemistry, 2009 - ASBMB
Hepatic lipid overloading mainly in the form of triglycerides is considered a prerequisite for the
development of nonalcoholic fatty liver disease (NAFLD). However, triglyceride accumulation
in the liver in response to lipid overflow may represent a protective mechanism against ...
Cited by 8 - Related articles - All 3 versions

Glucolipotoxicity of the pancreatic beta cell


V Poitout, J Amyot, M Semache, B Zarrouki, D … - BBA-Molecular and Cell …, 2009 - Elsevier
The concept of glucolipotoxicity refers to the combined, deleterious effects of elevated
glucose, and fatty acid levels on pancreatic beta-cell function and survival. Significant progress
has been made in recent years towards a better understanding of the cellular and ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Inhibition of stearoyl-coenzyme a desaturase 1 dissociates insulin resistance and …

- ahajournals.org
JM Brown, S Chung, JK Sawyer, C Degirolamo, HM … - Circulation, 2008 - Am Heart Assoc
Methods and Results— Antisense oligonucleotides were used to inhibit SCD1 in a mouse model
of hyperlipidemia and atherosclerosis (LDLr –/– Apob 100/100 ). In agreement with previous
reports, inhibition of SCD1 protected against diet-induced obesity, insulin resistance, and ...
Cited by 9 - Related articles - All 7 versions


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