E Kroon, LA Martinson, K Kadoya, AG Bang, OG … - Nature …, 2008 - novocell.com Development of a cell therapy for diabetes would be greatly aided by a renewable supply of
human ß-cells. Here we show that pancreatic endoderm derived from human embryonic stem
(hES) cells efficiently generates glucose-responsive endocrine cells after implantation ... Cited by 134 - Related articles - View as HTML - BL Direct - All 10 versions
- ►endojournals.org MC Jorgensen, J Ahnfelt-Ronne, J Hald, OD … - Endocrine …, 2007 - Endocrine Soc Pancreas morphogenesis and cell differentiation are highly conserved among vertebrates during
fetal development. The pancreas develops through simple budlike structures on the primitive
gut tube to a highly branched organ containing many specialized cell types. This review ... Cited by 37 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] WS Chung, DYR Stainier - Developmental cell, 2008 - Elsevier The cellular origin of signals that regulate pancreatic β cell induction is not clearly defined.
Here, we investigate the seeming paradox that Hedgehog/Smoothened signaling functions during
gastrulation to promote pancreatic β cell development in zebrafish, yet has an inhibitory ... Cited by 9 - Related articles - All 10 versions
- ►nih.gov C Haumaitre, O Lenoir, R Scharfmann - Molecular and Cellular …, 2008 - Am Soc Microbiol During pancreas development, transcription factors play critical roles in exocrine and endocrine
differentiation. Transcriptional regulation in eukaryotes occurs within chromatin and is influenced
by posttranslational histone modifications (eg, acetylation) involving histone deacetylases ... Cited by 6 - Related articles - All 4 versions
R Scharfmann - Endocrine development, 2007 - content.karger.com Abstract Understanding pancreas development is important for at least 3 reasons: first, from a
cognitive point of view, to understand the development of a complex organ, the pancreas;
next, because it is now clear that abnormal pancreas development can give rise to ... Cited by 2 - Related articles - BL Direct - All 5 versions
B Duvillie, V Stetsyuk, G Filhoulaud, G … - Biochemical Society …, 2008 - biochemsoctrans.org Understanding pancreatic development is important for at least three reasons: first, from a cognitive
point of view, to understand the development of a complex organ, the pancreas; next, because
it is now clear that abnormal pancreatic development can give rise to specific forms of ... Cited by 1 - Related articles - Cached - BL Direct - All 4 versions
B Duvillie, M Heinis, V Stetsyuk - Development of the Pancreas and …, 2007 - books.google.com Shield JPH, Scharfmann R (eds): Development of the Pancreas and Neonatal Diabetes. Endocr
Dev. Basel, Karger, 2007, vol 12, pp 46-54 In vivo and in vitro Techniques to Study Pancreas
Development and Islet Cell Function Bertrand Duvillie• Mylene Heinis• Volodymyr ... Cited by 1 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org [PDF] S Fontaniere, B Duvillie, R Scharfmann, C … - Journal of …, 2008 - Soc Endocrinology Page 1. 1 Tumour suppressor MENIN is essential for development of the pancreatic
endocrine cells Sandra Fontanière, Bertrand Duvillié, Raphaël Scharfmann, Christine
Carreira, Zhao-Qi Wang and Chang-Xian Zhang Université ... Cited by 1 - Related articles - All 3 versions
R Scharfmann, X Xiao, H Heimberg, J Mallet, P … - PLoS ONE, 2008 - pubmedcentral.nih.gov In both humans and rodents, glucose homeostasis is controlled by micro-organs called islets
of Langerhans composed of beta cells, associated with other endocrine cell types. Most of our
understanding of islet cell differentiation and morphogenesis is derived from rodent ... Cited by 1 - Related articles - All 6 versions
- ►ucsd.edu [PDF] N Jonckheere, E Mayes, HP Shih, B Li, O Lioubinski, X … - Developmental biology, 2008 - Elsevier Pygopus has recently been identified in Drosophila as an essential component of the nuclear
complex required for canonical Wnt signaling. Here, we have investigated the role of the mammalian
pygopus ortholog, mPygo2, in pancreas development. We show that a null mutation of ... Cited by 1 - Related articles - All 5 versions