VE Degtyar, MW Allersma, D Axelrod, … - Proceedings of the …, 2007 - National Acad Sciences The state of secretory granules immediately before fusion with the plasma membrane is
unknown, although the granules are generally assumed to be stably bound (docked). We had
previously developed methods using total internal reflection fluorescence microscopy and ... Cited by 9 - Related articles - BL Direct - All 6 versions
S Barg, A Lindqvist, S Obermuller - Biochemical Society …, 2008 - biochemsoctrans.org Biphasic insulin secretion is required for proper insulin action and is observed not only in
vivo, but also in isolated pancreatic islets and even single β-cells. Late events in the granule
life cycle are thought to underlie this temporal pattern. In the last few years, we have ... Cited by 4 - Related articles - Cached - BL Direct - All 4 versions
- ►physiology.org AV Matveyenko, JD Veldhuis, PC … - American Journal of …, 2008 - Am Physiological Soc It has previously been shown that insulin is secreted in discrete secretory bursts by sampling
directly from the portal vein in the dog and humans. Deficient pulsatile insulin secretion is the
basis for impaired insulin secretion in type 2 diabetes. However, while novel genetically ... Cited by 1 - Related articles - All 4 versions
- ►nih.gov MA Ravier, T Tsuboi, GA Rutter - Methods, 2008 - Elsevier Ca 2+ ions are the most ubiquitous second messenger found in all cells, and play a significant
role in controlling regulated secretion from neurons, endocrine, neuroendocrine and exocrine
cells. Here, we describe microscopic techniques to image regulated secretion, a target of ... Related articles - All 6 versions
J Sågetorp - uu.diva-portal.org Dissertation presented at Uppsala University to be publicly examined in B21, BMC, Husargatan
3, Uppsala, Saturday, March 21, 2009 at 09:15 for the degree of Doctor of Philosophy (Faculty
of Medicine). The examination will be conducted in Swedish. ... Abstract Sagetorp, J. ... Related articles - View as HTML - All 2 versions
V Shanmuganathan - 2008 - digitallibrary.usc.edu Page 1. A NOVEL CONSTRUCT TO STUDY THE PULSATILITY OF INSULIN
SECRETION IN SINGLE CELLS, ISLETS, AND WHOLE PANCREAS by
Vivekanandan Shanmuganathan A Thesis Presented to the FACULTY OF ... Related articles - View as HTML - All 2 versions
M Braun, R Ramracheya, PR Johnson, … - Annals of the New …, 2009 - interscience.wiley.com Pancreatic β-cells secrete insulin in response to elevated blood glucose via Ca 2+ -dependent
fusion of secretory granules with the plasma membrane (regulated exocytosis). While exocytosis
has been extensively investigated in rodent β-cells, studies on human β-cells are scarce. ... Related articles - All 4 versions
S Misler - Advances in Physiology Education, 2009 - Am Physiological Soc Stimulus-secretion coupling (SSC) in endocrine cells remains underappreciated as a subject
for the study/teaching of general physiology. In the present article, we review key new
electrophysiological, electrochemical, and fluorescence optical techniques for the study of ... Related articles - All 2 versions