- ►diabetesjournals.org R Granata, F Settanni, D Gallo, L Trovato, L Biancone, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Obestatin showed specific binding on HIT-T15 and INS-1E β-cells, bound to
glucagon-like peptide-1 receptor (GLP-1R), and recognized ghrelin binding sites. Obestatin exerted
proliferative, survival, and antiapoptotic effects under serum-deprived conditions and ... Cited by 27 - Related articles - BL Direct - All 3 versions
S Marzorati, A Pileggi, C Ricordi - Expert Opin. Biol. Ther., 2007 - informahealthcare.com Significant progress has been made in the field of β-cell replacement therapies by islet transplantation
in patients with unstable Type 1 diabetes mellitus (T1DM). Recent clinical trials have shown that
islet transplantation can reproducibly lead to insulin independence when adequate islet ... Cited by 11 - Related articles - BL Direct - All 6 versions
R Granata, F Settanni, D Gallo, L Trovato, L Biancone, … - Diabetes, 2008 - Am Diabetes Assoc Page 1. Obestatin Promotes Survival of Pancreatic -Cells and Human Islets and Induces
Expression of Genes Involved in the Regulation of -Cell Mass and Function Riccarda Granata,
1,2 Fabio Settanni, 1,2 Davide Gallo, 1,2 Letizia Trovato, 1,2 Luigi Biancone, 2 ... Cited by 7 - Related articles
S Merani, C Toso, J Emamaullee, AMJ … - British Journal of …, 2008 - ingentaconnect.com Background: Since the first report of successful pancreatic islet transplantation to reverse hyperglycaemia
in diabetic rodents, there has been great interest in determining the optimal site for
implantation. Although the portal vein remains the most frequently used site clinically, it is ... Cited by 7 - Related articles - All 4 versions
JA Emamaullee, J Davis, R Pawlick, C Toso, S Merani, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Clinical islet transplantation can provide insulin independence in patients with
type 1 diabetes, but chronic graft failure has been observed. This has been attributed in part
to loss of ≥60% of the transplanted islets in the peritransplant period, resulting in a ... Cited by 5 - Related articles - All 4 versions
- ►endojournals.org S Merani, W Truong, JA Emamaullee, C Toso, LB … - Endocrinology, 2008 - Endocrine Soc The current scarcity of high-quality deceased pancreas donors prevents widespread application
of islet transplantation for treatment of labile type 1 diabetes mellitus. Opportunities for the improvement
of current techniques include optimization of islet isolation and purification, use of culture ... Cited by 5 - Related articles - All 4 versions
SH Lee, E Hao, AY Savinov, I Geron, AY Strongin, P … - Transplantation, 2009 - journals.lww.com Transplantation. Wolters Kluwer Health | Lippincott Williams & Wilkins. All Issues. ... Cited by 2 - Related articles - All 5 versions
C Toso, V Serre-Beinier, J Emamaullee, S Merani, M … - Transplantation, 2008 - journals.lww.com Macrophage migration inhibitory factor (MIF) is a proin- flammatory cytokine expressed by numerous
cells and tissues throughout the body. It is associated with many immuno-inflammatory
disorders, including sepsis, adult re- spiratory distress syndrome, glomerulonephritis, ... Cited by 1 - Related articles - All 2 versions
HE Thomas, MD McKenzie, E Angstetra, PD Campbell, … - Apoptosis - Springer Abstract Apoptosis of beta cells is a feature of both type 1 and type 2 diabetes as well as loss
of islets after trans- plantation. In type 1 diabetes, beta cells are destroyed by immunological
mechanisms. In type 2 diabetes abnormal levels of metabolic factors contribute to beta ... Cited by 2 - Related articles - All 2 versions
JA Emamaullee, S Merani, C Toso, T Kin, F Al-Saif, W … - Endocrinology, 2009 - Endocrine Soc Although insulin independence is maintained in most islet recipients at 1 yr after transplant, extended
follow-up has revealed that many patients will eventually require insulin therapy. Previous studies
have shown that islet autografts are prone to chronic failure in large animals and humans, ... Cited by 1 - Related articles - All 3 versions
