- ►pnas.org CS Choi, DE Befroy, R Codella, S Kim, … - Proceedings of the …, 2008 - National Acad Sciences Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α has been shown to play critical
roles in regulating mitochondria biogenesis, respiration, and muscle oxidative phenotype.
Furthermore, reductions in the expression of PGC-1α in muscle have been implicated in ... Cited by 17 - Related articles - All 7 versions
- ►jlr.org Y Takahashi, N Ohoka, H Hayashi, R Sato - The Journal of Lipid Research, 2008 - ASBMB In the course of an effort to identify the regulators for peroxisome proliferator-activated receptor
(PPAR )-dependent perilipin gene expression, we found that tribbles homolog 3 (TRB3), containing
a single kinase domain without enzymatic activity, downregulates PPAR transcriptional ... Cited by 7 - Related articles - All 4 versions
- ►ahajournals.org F Andreozzi, G Formoso, S Prudente, ML … - … , and vascular biology, 2008 - Am Heart Assoc From the Department of Experimental and Clinical Medicine (FA, MLH, GS), University Magna
Græcia of Catanzaro, Catanzaro, Italy; Department of Medicine and Aging Sciences (GF,
AC), University "G. d'Annunzio", Aging Research Center, Ce.SI, "G. d'Annunzio" University ... Cited by 6 - Related articles - All 8 versions
J Ding, S Kato, K Du - Experimental Cell Research, 2008 - Elsevier TRB3 is a pseudokinase whose expression is regulated during stress response and changing
of nutrient status. TRB3 negatively regulates Akt activation and noticeably, TRB3 expression
is induced by insulin. Here, we sought to determine the dynamic relationship between ... Cited by 5 - Related articles - All 3 versions
S Prudente, D Scarpelli, M Chandalia, YY … - Journal of Clinical …, 2009 - Endocrine Soc Context: The prevalence of type 2 diabetes (T2D), particularly among young adults, has been
rising steadily during the past 2 decades. T2D, especially in its early-onset subtype, is under
genetic control. TRIB3 inhibits insulin-stimulated Akt phosphorylation and subsequent ... Cited by 3 - Related articles - All 4 versions
D Örd - 2008 - dspace.utlib.ee The dissertation is accepted for the commencement of the degree of Doctor of Philosophy (in
Molecular Biology) on June 6, 2008 by the Council of the Institute of Molecular and Cell
Biology, University of Tartu. ... Supervisors: Tõnis Örd, PhD, Senior Scientist, Estonian ... Cited by 2 - Related articles - All 3 versions
M Takasato, C Kobayashi, K Okabayashi, H … - … and Biophysical Research …, 2008 - Elsevier Glomeruli comprise an important filtering apparatus in the kidney and are derived from the metanephric
mesenchyme. A nuclear protein, Sall1, is expressed in this mesenchyme, and we previously
reported that Trb2, a mouse homolog of Drosophila tribbles, is expressed in the ... Related articles - All 3 versions
Z Shi, J Liu, Q Guo, X Ma, L Shen, S Xu, H Gao, X Yuan … - Endocrine, 2009 - Springer Abstract Background TRB3, a human homolog of Dro- sophila Tribbles, has been shown as a
critical negative regulator of Akt (also known as protein kinase B), which is a key component
in insulin signaling. In addition, TRB3 is another PPAR-target gene and functions as an ... Related articles - All 2 versions
I Kachko, A Maissel, L Mazor, R Ben-Romano, RT … - Endocrinology, 2009 - Endocrine Soc Adipocyte insulin resistance can be caused by proximal insulin signaling defects but also from
postreceptor mechanisms, which in large are poorly characterized. Adipocytes exposed for 18
h to the HIV protease inhibitor nelfinavir manifest insulin resistance characterized by ... Related articles - All 3 versions
