KD Taylor, JM Norris, JI Rotter - Diabetes, 2007 - Am Diabetes Assoc This year marks the application of the next gene-finding tool to the study of type 2 diabetes, the
genome-wide association study (GWA). This type of study is the logical extension of the candidate
gene association study, an approach in which a few (1–20 or so) single nucleotide ... Cited by 3 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org L Ma, RL Hanson, LN Que, AMG Cali, M Fu, JL Mack, … - Diabetes, 2007 - Am Diabetes Assoc A prior genome-wide linkage scan in Pima Indians indicated a young-onset (aged <45
years) type 2 diabetes susceptibility locus on chromosome 1q21-q23. ARHGEF11, which encodes
the Rho guanine nucleotide exchange factor 11, was analyzed as a positional candidate ... Cited by 3 - Related articles - BL Direct - All 8 versions
L Muller… - Diabetes, 2007 - Am Diabetes Assoc RESULTS— A novel G/A variant in the 3′-UTR was associated with young-onset type 2 diabetes
(odds ratio 2.09 per copy of the G-allele [95% CI 1.31–3.33], adjusted P = 0.001) and had an
effect on the evidence for linkage at chromosome 1q21-25 (P = 0.004). Among 372 ... Cited by 2 - Related articles - BL Direct - All 3 versions
KD Taylor, JM Norris, JI Rotter - Diabetes, 2007 - Am Diabetes Assoc I t has long been appreciated that there is a genetic component to type 2 diabetes, but progress
in gene finding has been slow because the genetic compo- nent is complex. Accumulating data
on various diabetes-related phenotypes suggest that so-called “type 2 diabetes” is likely a ... Cited by 1 - Related articles
- ►uni-leipzig.de [PDF] Y Böttcher, D Schleinitz, A Tönjes, M Blüher, M … - Journal of Human …, 2008 - Springer Page 1. SHORT COMMUNICATION R1467H variant in the rho guanine nucleotide
exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance
and type 2 diabetes in German Caucasians Yvonne Böttcher ... Related articles - BL Direct - All 4 versions
- ►eje-online.org C Holzapfel, N Klopp, H Grallert, C Huth, C Gieger, C … - European Journal of …, 2007 - EFES Methods: Sequencing of Tyr1306Cys, which was of functional relevance in Pima Indians, in 48
randomly selected individuals and genotyping of 11 additional LARG SNPs in 1653 subjects
were performed. Four linkage disequilibrium (LD) blocks (r 2 0.8) were established and ... Related articles - BL Direct - All 7 versions
YL Muller, RL Hanson, C Zimmerman, I Harper, J … - DIABETES, 2007 - Am Diabetes Assoc Variants in the Ca v 2.3 ( 1E) Subunit of ... Voltage-Activated Ca 2 Channels Are Associated
With ... Insulin Resistance and Type 2 Diabetes in Pima Indians ... Yunhua Li Muller, Robert
L. Hanson, Collin Zimmerman, Inge Harper, Jeff Sutherland, Sayuko Kobes, the ... Related articles
YL Muller, RL Hanson, C Zimmerman, I Harper, J … - DIABETES, 2007 - assets0.pubget.com Variants in the Cav 2.3 ( 1E) Subunit of ... Voltage-Activated Ca 2 Channels Are Associated With ... Insulin Resistance and Type 2 Diabetes in Pima Indians ... Yunhua Li Muller, Robert L.
Hanson, Collin Zimmerman, Inge Harper, Jeff Sutherland, Sayuko Kobes, the ... Related articles - View as HTML
WC Knowler, C Bogardus, LJ Baier - Am Diabetes Assoc Variants in the Cav2.3 (α1E) Subunit of Voltage-Activated Ca2+ ... Channels are Associated
with Insulin Resistance and Type 2 ... Yunhua Li Muller, Robert L. Hanson, Collin
Zimmerman, Inge Harper, Jeff Sutherland, Sayuko Kobes, The International Type 2 ... Related articles
SH Kim, SH Ghil - 대한의생명과학회지, 2007 - dbpia.co.kr Heterotrimeric GTP binding proteins (G proteins) mediate signal generated by neurotransmitter
and hormones. Among all G proteins, Go is the most abundant in brain but its role in brain is
not clearly understood. To determine the function of the alpha subunit of Go (Goα), we ... Related articles