- ►physiology.org DB Savage, KF Petersen, GI Shulman - Physiological reviews, 2007 - Am Physiological Soc Although abnormal glucose metabolism defines type 2 diabetes mellitus (T2DM) and
accounts for many of its symptoms and complications, efforts to understand the
pathogenesis of T2DM are increasingly focused on disordered lipid ... Cited by 111 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org J Kim, Y Wei, JR Sowers - Circulation research, 2008 - Am Heart Assoc Insulin resistance is characteristic of obesity, type 2 diabetes, and components
of the cardiometabolic syndrome, including hypertension and dyslipidemia, that
collectively contribute to a substantial risk for cardiovascular disease. ... Cited by 49 - Related articles - All 6 versions
EW Kraegen, GJ Cooney - Current Opinion in Lipidology, 2008 - journals.lww.com Introduction The hypothesis that insulin resistance is related to tri- glyceride
accumulation in muscle and liver dates back to studies of 15–20 years ago
showing that triglyceride accumulates in muscle of high fat-fed rats, ... Cited by 25 - Related articles - BL Direct - All 2 versions
- ►cnfindpark.cn JO Holloszy - American Journal of Clinical Nutrition, 2009 - Am Soc Nutrition Patients with type 2 diabetes, insulin-resistant obese individuals, and
insulin-resistant offspring of patients with diabetes have 30% less mitochondria
in their skeletal muscles than age-matched healthy controls. It has been ... Cited by 19 - Related articles - All 6 versions
- ►pnas.org CS Choi, DE Befroy, R Codella, S Kim, RM … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α has been
shown to play critical roles in regulating mitochondria biogenesis, respiration,
and muscle oxidative phenotype. Furthermore, reductions in the expression ... Cited by 16 - Related articles - All 7 versions
VB Schrauwen-Hinderling, M Roden, ME Kooi … - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Recent findings: In-vivo magnetic resonance spectroscopy allows assessment of
mitochondrial functionality from adenosine triphosphate flux in the
nonexercising state and from phosphocreatine recovery from (sub)maximal ... Cited by 13 - Related articles - BL Direct - All 3 versions
N Turner, LK Heilbronn - Trends in Endocrinology & Metabolism, 2008 - Elsevier Insulin resistance is a key defect associated with obesity and type-2 diabetes.
The precise factors that lead to insulin resistance have not been elucidated
fully, but there is a strong association between insulin resistance and ... Cited by 13 - Related articles - All 5 versions
- ►physicaltherapyjournal.com LP Turcotte, JS Fisher - Physical Therapy, 2008 - physicaltherapyjournal.com The purpose of this review is to provide information about the role of exercise
in the prevention of skeletal muscle insulin resistance, that is, the inability
of insulin to properly cause glucose uptake into skeletal muscle. Insulin ... Cited by 11 - Related articles - All 31 versions
- ►endojournals.org AE Civitarese, E Ravussin - Endocrinology, 2008 - Endocrine Soc MORE THAN 300 million individuals worldwide are projected to be afflicted with
type 2 diabetes mellitus (T2DM) by the year 2025 (1). Other comorbidities that
cluster with diabetes include obesity, dyslipidemia, hypertension, and ... Cited by 11 - Related articles - BL Direct - All 6 versions
Y Ido - Antioxidants & Redox Signaling, 2007 - liebertonline.com C HEMICAL REACTIONS involving movement of electrons are called redox reactions
(reduction and oxidation). This review will describe characteristics of redox
abnormali- ties observed in diabetes. Diabetes affects a number of tissues ... Cited by 11 - Related articles - BL Direct - All 5 versions
