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Scholar Results 1 - 10 of 12 citing Arikawa: Effects of insulin replacements, inhibitors of angiotensin, and PKCβ's actions.... (0.11 sec) 

High glucose induces adipogenic differentiation of muscle-derived stem cells

- pnas.org
P Aguiari, S Leo, B Zavan, V Vindigni, A … - Proceedings of the …, 2008 - National Acad Sciences
Regeneration of mesenchymal tissues depends on a resident stem cell population, that in most
cases remains elusive in terms of cellular identity and differentiation signals. We here show that
primary cell cultures derived from adipose tissue or skeletal muscle differentiate into ...
Cited by 20 - Related articles - BL Direct - All 10 versions

Mechanisms of disease: the oxidative stress theory of diabetic neuropathy


C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & …, 2008 - Springer
Abstract Diabetic neuropathy is the most common com- plication of diabetes, affecting 50% of
diabetic patients. Currently, the only treatment for diabetic neuropathy is glucose control and
careful foot care. In this review, we discuss the idea that excess glucose overloads the ...
Cited by 11 - Related articles - All 2 versions

Protein kinase C beta inhibitors: a new therapeutic target for diabetic nephropathy …

- duanessolution.com
S Budhiraja, J Singh - Fundamental & Clinical Pharmacology, 2008 - pt.wkhealth.com
Diabetic nephropathy (DN) has emerged as the major causative pathology in patients entering
end-stage renal disease (ESRD) worldwide and it is responsible for 30-40% of all ESRD
cases. Treatments for DN are centered on control of hyperglycemia and blood pressure ...
Cited by 6 - Related articles - BL Direct - All 6 versions

Captopril normalizes insulin signaling and insulin-regulated substrate metabolism …

- endojournals.org
I Tabbi-Anneni, J Buchanan, RC Cooksey, ED Abel - Endocrinology, 2008 - Endocrine Soc
The goal of this study was to determine whether inhibiting the renin-angiotensin system would
restore insulin signaling and normalize substrate use in hearts from obese ob/ob mice. Mice
were treated for 4 wk with Captopril (4 mg/kg·d). Circulating levels of free fatty acids, ...
Cited by 6 - Related articles - All 4 versions

Mitochondrial uncoupling protein 3 and its role in cardiac-and skeletal muscle …


M Nabben, J Hoeks - Physiology & Behavior, 2008 - Elsevier
Uncoupling protein 3 (UCP3), is primarily expressed in skeletal muscle mitochondria and has
been suggested to be involved in mediating energy expenditure via uncoupling, hereby dissipating
the mitochondrial proton gradient necessary for adenosine triphosphate (ATP) synthesis. ...
Cited by 3 - Related articles - All 3 versions

Diacylglycerol kinase ζ inhibits myocardial atrophy and restores cardiac …


O Bilim, Y Takeishi, T Kitahara, T Arimoto, T … - Cardiovascular …, 2008 - cardiab.com
We examined transgenic mice with cardiac-specific overexpression of DGKζ (DGKζ-TG) compared
to wild type (WT) mice in streptozotocin-induced (STZ, 150 mg/kg) diabetic and nondiabetic
conditions. After 8 weeks, decreases in heart weight and heart weight/body weight ratio in ...
Cited by 3 - Related articles - Cached - All 10 versions

Inhibition of Protein Kinase C-{beta} by Ruboxistaurin Preserves Cardiac Function …


KA Connelly, DJ Kelly, Y Zhang, DL Prior, A … - Circulation: Heart …, 2009 - Am Heart Assoc
Background— Heart failure is a common cause of morbidity and mortality in diabetic patients
that frequently manifests in the absence of impaired left ventricular systolic function. In contrast
to the strong evidence base for the treatment of systolic heart failure, the treatment of ...
Related articles - All 4 versions

Diabetic cardiomyopathy


O Asghar, A Al-Sunni, K Khavandi, A Khavandi, S … - Clinical Science, 2009 - submit.clinsci.org
Abbreviations: ACE, angiotensin-converting enzyme; ACEI, ACE inhibitor; AGE, advanced glycosylation
end-product; AngII, angiotensin II; AT 1 , AngII type 1 receptor; ARB, AT 1 receptor blocker;
BK, bradykinin; BNP, brain natriuretic peptide; BP, blood pressure; B1R, B1-receptor; ...
Related articles - Cached - All 4 versions

Diabetic cardiomyopathy–a distinct disease?


K Khavandi, A Khavandi, O Asghar, A Greenstein, S … - Best Practice & Research …, 2009 - Elsevier
Diabetic individuals have a significantly increased likelihood of developing cardiovascular
disease. Whilst part of this association is explained by the presence of concomitant risk
factors, large epidemiological studies have consistently reported diabetes as a strong risk ...
Related articles - All 2 versions

Inhibition of PKC-{beta} by Ruboxistaurin Preserves Cardiac Function and …


KA Connelly, DJ Kelly, Y Zhang, DL Prior, A … - Circulation: Heart …, 2009 - Am Heart Assoc
Short Title: PKC inhibition in diabetic diastolic heart failure ... Kim A Connelly, MBBS
PhD1,2; Darren J Kelly, PhD 2; Yuan Zhang, MBBS 2; David ... L Prior, MBBS PhD 3; Andrew
Advani, BSc MBChb PhD MRCP 1; Alison J Cox, BSc ... 2; Kerri Thai, BSc1; Henry Krum, ...
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