- ►pnas.org G Lettre, VG Sankaran, MAC Bezerra, AS … - Proceedings of the …, 2008 - National Acad Sciences Sickle cell disease (SCD) is a debilitating monogenic blood disorder with a highly variable phenotype
characterized by severe pain crises, acute clinical events, and early mortality. Interindividual
variation in fetal hemoglobin (HbF) expression is a known and potentially heritable ... Cited by 26 - Related articles - All 6 versions
S Li, RJF Loos - Current Opinion in Lipidology, 2008 - journals.lww.com Purpose of review: Over the past two decades serious efforts has been invested in the search
for genes that predispose to common obesity, but progress has been slow and success
limited. Genome-wide association, however, has revived optimism. Here we review ... Cited by 14 - Related articles - BL Direct - All 2 versions
- ►171.66.122.45 CD Campbell, A Kirby, J Nemesh, MJ Daly, JN … - Genome Research, 2008 - 171.66.122.45 There are widespread, genetically determined differences in gene expression. However, methods
that compare transcript levels between individuals are subject to trans-acting effects and environmental
differences. By looking at allele-specific expression in the F1 progeny of inbred mice, we ... Cited by 8 - Related articles - BL Direct - All 9 versions
A Viardot, LK Heilbronn, H Herzog, S Gregersen, … - International Journal of …, 2008 - nature.com Gut-derived hormone peptide YY (PYY) is low in subjects with obesity and type 2 diabetes
(T2D). However, it is unknown whether this is a primary defect or a consequence of metabolic
disturbances. In this study, we aimed to assess whether low fasting and postprandial PYY ... Cited by 3 - Related articles - All 3 versions
CC Elbers, KR van Eijk, L Franke, F Mulder, YT … - Genet …, 2009 - interscience.wiley.com Several genome-wide association studies (GWAS) have been published on various complex
diseases. Although, new loci are found to be associated with these diseases, still only very little
of the genetic risk for these diseases can be explained. As GWAS are still underpowered ... Cited by 2 - Related articles - All 2 versions
RJF Loos, MRCE Unit - British Journal of Clinical Pharmacology, 2009 - interscience.wiley.com For the last 15 years, candidate gene and genome-wide linkage studies have been the two main
genetic epidemiological approaches to identify genetic loci for common traits, yet, progress has
been slow and success limited. Only recently candidate gene studies have starting to ... Related articles
JV van Vliet-Ostaptchouk, MH Hofker, YT van … - Obesity …, 2009 - interscience.wiley.com We summarize current knowledge on the physiological role of the hypothalamus in body-weight
regulation and review genetic studies on the hypothalamic candidate genes in relation to
obesity. Together, data from functional and genetic studies as well as the new, common, ... Related articles
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SER. D OSA - TOM. 850 MEDICA - ODONTOLOGICA TURUN YLIOPISTO Turku 2009
NEUROPEPTIDE Y AT THE CELLULAR LEVEL Studies on PreproNPY L7P Polymorphism ... Related articles - View as HTML
LJ Goodrich, LM Yerges-Armstrong, I Miljkovic, CS … - Calcified Tissue … - Springer Abstract Neuropeptide Y (NPY) is a physiological can- didate gene for the regulation of body
weight and has more recently been implicated in regulating bone mass. The current study sought
to test if inherited variation in NPY might influence BMD in a population of ...
F Abbatini, M Rizzello, G Casella, G Alessandri, D … - Surgical Endoscopy - Springer Abstract Background This study aimed to compare the efficacy of laparoscopic sleeve gastrectomy
(SG) with that of laparo- scopic gastric bypass (GBP) and laparoscopic adjustable gastric banding
(AGB) for glucose homeostasis in mor- bidly obese subjects with type 2 diabetes mellitus ( ...