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Scholar Results 1 - 10 of about 13 citing Prudente: A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated.... (0.11 sec) 

Aquaporin 7 Is a {beta}-Cell Protein and Regulator of Intraislet Glycerol Content …

- nih.gov
K Matsumura, BHJ Chang, M Fujimiya, W … - Molecular and Cellular …, 2007 - Am Soc Microbiol
To investigate if intracellular glycerol content plays a role in the regulation of insulin secretion
in pancreatic ß cells, we studied the expression of the glycerol channels, or
aquaglyceroporins, encoded by the aquaporin 3 (Aqp3), Aqp7, and Aqp9 genes in mouse ...
Cited by 13 - Related articles - BL Direct - All 7 versions

Adipose tissue expression of the glycerol channel aquaporin-7 gene is altered in …

- endojournals.org
V Ceperuelo-Mallafré, M Miranda, MR Chacón, … - Journal of Clinical …, 2007 - Endocrine Soc
Results: Severely obese women showed lower AQP7 expression levels compared with lean
and nonseverely obese (P < 0.001). Moreover, circulating glycerol concentration was lower in
severely obese subjects, but no correlation with AQP7 adipose tissue expression was ...
Cited by 10 - Related articles - BL Direct - All 6 versions

Influence of morbid obesity and insulin resistance on gene expression levels of …


V Catalán, J Gómez-Ambrosi, C Pastor, F Rotellar, C … - Obesity Surgery, 2008 - Springer
Abstract Background Glycerol production and its efflux from adipo- cytes to the liver are key to
modulate lipid and glucose homeostasis. Aquaporin 7 (AQP7) is an aquaglyceroporin that acts
as the adipose glycerol channel, whereas aquaporin 9 (AQP9) is the specific channel ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Present and future therapeutic strategies in non-alcoholic fatty liver disease


G Calamita, P Portincasa - Expert Opinion on Therapeutic …, 2007 - Informa Pharma Science
Non-alcoholic fatty liver disease (NAFLD) is found in individuals who do not drink or abuse alcohol
and represents a significant health burden for the general community. NAFLD is often associated
with one or more features of the metabolic syndrome and has potential for evolution ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Advances in adipose tissue metabolism


M Lafontan - International Journal of Obesity, 2008 - nature.com
This review will focus on the recent findings in adipose tissue metabolism with special attention
to human adipocyte biology and physiology. There are major advances stemming from the concomitant
results obtained from studies on mature human adipocytes, human preadipocytes ...
Cited by 6 - Related articles - All 3 versions

The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol …

- cardiovascres.org
T Hibuse, N Maeda, H Nakatsuji, Y … - Cardiovascular …, 2009 - cardiovascres.oxfordjournals.org
Aims: Cardiomyocytes require fatty acids and glucose for energy production. However, other
nutrients and substrates that may serve as possible candidates for a cardiac energy source have
not been fully studied. Several reports showed that a moderate expression of aquaporin 7 ...
Cited by 2 - Related articles - All 4 versions

Knock-Out Models Reveal New Aquaporin Functions

- bsz-bw.de [PDF] 
AS Verkman - Handbook of experimental pharmacology, 2009 - Springer
Abstract Knockout mice have been informative in the discovery of unexpected biological functions
of aquaporins. Knockout mice have confirmed the predicted roles of aquaporins in transepithelial
fluid transport, as in the urinary concentrat- ing mechanism and glandular fluid secretion. ...
Cited by 1 - Related articles - All 4 versions

Role of Aquaporin-7 and Aquaporin-9 in Glycerol Metabolism; Involvement in …


N Maeda, T Hibuse, T Funahashi - Handbook of experimental pharmacology, 2009 - Springer
1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234 2 Characteristics
of Adipocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235 3 AQP7. . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236 3.1 Molecular ...
Cited by 1 - Related articles - All 3 versions

Aquaporins: translating bench research to human disease


AS Verkman - Journal of Experimental Biology, 2009 - jeb.biologists.org
There is considerable potential for translating knowledge of aquaporin structure, function and
physiology to the clinic. One area is in aquaporin-based diagnostics. The discovery of AQP4
autoantibodies as a marker of the neuromyelitis optica form of multiple sclerosis has ...
Related articles - All 2 versions

Aquaporin 7 Is a $# x003b2;-Cell Protein and Regulator of Intraislet Glycerol …


K Matsumura, BHJ Chang, M Fujimiya, W Chen, … - Molecular and Cellular …, 2007 - ukpmc.ac.uk
To investigate if intracellular glycerol content plays a role in the regulation of insulin secretion
in pancreatic β cells, we studied the expression of the glycerol channels, or
aquaglyceroporins, encoded by the aquaporin 3 (Aqp3), Aqp7, and Aqp9 genes in mouse ...
Related articles - All 2 versions


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