- ►nih.gov S Banerjee, K Saito, M Ait-Goughoulte, K … - The Journal of Virology, 2008 - jvi.highwire.org Chronic hepatitis C virus (HCV) infection has a significantly increased
prevalence of type 2 diabetes mellitus (T2DM). Insulin resistance is a critical
component of T2DM pathogenesis. Several mechanisms are likely to be ... Cited by 18 - Related articles - BL Direct - All 9 versions
S Boura-Halfon, Y Zick - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc Insulin signaling at target tissues is essential for growth and development and
for normal homeostasis of glucose, fat, and protein metabolism. Control over
this process is therefore tightly regulated. It can be achieved by a ... Cited by 6 - Related articles - All 3 versions
S Fröjdö, H Vidal, L Pirola - BBA-Molecular Basis of Disease, 2009 - Elsevier A generally accepted view posits that insulin resistant condition in type 2
diabetes is caused by defects at one or several levels of the insulin-signaling
cascade in skeletal muscles, adipose tissue and liver, that quantitatively ... Cited by 4 - Related articles - All 2 versions
C Weigert, M Kron, H Kalbacher, AK Pohl, H … - Molecular Endocrinology, 2008 - Endocrine Soc Transduction of the insulin signal is mediated by multisite Tyr and Ser/Thr
phosphorylation of the insulin receptor substrates (IRSs). Previous studies on
the function of single-site phosphorylation, particularly phosphorylation ... Cited by 2 - Related articles - All 3 versions
S Banerjee, K Saito, M Ait-Goughoulte, K … - Journal of Virology, 2007 - Am Soc Microbiol Page 1. REVISED December 9, 2007 HEPATITIS C VIRUS CORE PROTEIN UPREGULATES
SERINE PHOSPHORYLATION OF IRS-1 AND IMPAIRS DOWNSTREAM AKT/PKB ... Cited by 3 - Related articles
JF Tanti, J Jager - Current Opinion in Pharmacology, 2009 - Elsevier Insulin receptor substrates (IRS) serine phosphorylation is a time-controlled
physiological feedback mechanism in insulin signaling that is hijacked by
metabolic and inflammatory stresses to promote insulin resistance. Kinases, ... Cited by 1 - Related articles - All 2 versions