- ►ahajournals.org J Kim, Y Wei, JR Sowers - Circulation research, 2008 - Am Heart Assoc Insulin resistance is characteristic of obesity, type 2 diabetes, and components
of the cardiometabolic syndrome, including hypertension and dyslipidemia, that
collectively contribute to a substantial risk for cardiovascular disease. ... Cited by 49 - Related articles - All 6 versions
JW Eriksson - FEBS letters, 2007 - Elsevier The metabolic syndrome is a cluster of cardiovascular risk factors, and visceral
adiposity is a central component that is also strongly associated with insulin
resistance. Both visceral obesity and insulin resistance are important risk ... Cited by 24 - Related articles - All 12 versions
VB Schrauwen-Hinderling, M Roden, ME Kooi … - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Recent findings: In-vivo magnetic resonance spectroscopy allows assessment of
mitochondrial functionality from adenosine triphosphate flux in the
nonexercising state and from phosphocreatine recovery from (sub)maximal ... Cited by 13 - Related articles - BL Direct - All 3 versions
N Turner, LK Heilbronn - Trends in Endocrinology & Metabolism, 2008 - Elsevier Insulin resistance is a key defect associated with obesity and type-2 diabetes.
The precise factors that lead to insulin resistance have not been elucidated
fully, but there is a strong association between insulin resistance and ... Cited by 13 - Related articles - All 5 versions
- ►physicaltherapyjournal.com LP Turcotte, JS Fisher - Physical Therapy, 2008 - physicaltherapyjournal.com The purpose of this review is to provide information about the role of exercise
in the prevention of skeletal muscle insulin resistance, that is, the inability
of insulin to properly cause glucose uptake into skeletal muscle. Insulin ... Cited by 11 - Related articles - All 31 versions
- ►physiology.org GP Holloway, CGR Perry, A Thrush, GJF … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Reduced skeletal muscle mitochondrial content and fatty acid oxidation are
associated with obesity and insulin resistance. Although the exact mechanisms
remain elusive, this may result from impaired mitochondrial biogenesis or ... Cited by 10 - Related articles - All 3 versions
- ►eje.org HM De Feyter, NMA van den Broek, SFE Praet, … - European Journal of Endocrinology, 2008 - eje.org Objective: Several lines of evidence support a potential role of skeletal muscle
mitochondrial dysfunction in the pathogenesis of insulin resistance and/or type
2 diabetes. However, it remains to be established whether mitochondrial ... Cited by 10 - Related articles - BL Direct - All 5 versions
EJ Anderson, ME Lustig, KE Boyle, TL … - The Journal of Clinical Investigation, 2009 - pubmedcentral.nih.gov High dietary fat intake leads to insulin resistance in skeletal muscle, and this
represents a major risk factor for type 2 diabetes and cardiovascular disease.
Mitochondrial dysfunction and oxidative stress have been implicated in the ... Cited by 12 - Related articles - All 3 versions
J Hoeks, JJ Briedé, J de Vogel, G Schaart, … - FEBS letters, 2008 - Elsevier A high intake of dietary fat has been suggested to diminish mitochondrial
functioning in skeletal muscle, possibly attributing to muscular fat
accumulation. Here we show however, that an 8-week high-fat dietary ... Cited by 9 - Related articles - All 4 versions
- ►diabetesjournals.org E Phielix, VB Schrauwen-Hinderling, M … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Insulin-stimulated glucose disposal was lower in diabetic patients
compared with control subjects (11.2 ± 2.8 vs. 28.9 ± 3.7 μmol · kg −1
fat-free mass · min −1 , respectively; P = 0.003), with intermediate ... Cited by 8 - Related articles - All 4 versions
