- ►diabetesjournals.org PD Cani, R Bibiloni, C Knauf, A Waget, AM Neyrinck, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We found that changes of gut microbiota induced by an antibiotic treatment reduced
metabolic endotoxemia and the cecal content of LPS in both high-fat–fed and ob/ob mice. This
effect was correlated with reduced glucose intolerance, body weight gain, fat mass ... Cited by 60 - Related articles - All 5 versions
- ►ucl.ac.be [PDF] PD Cani, AM Neyrinck, F Fava, C Knauf, RG Burcelin, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Recent evidence suggests that a particular gut microbial community
may favour occurrence of the metabolic diseases. Recently, we reported that high-fat (HF) feeding
was associated with higher endotoxaemia and lower Bifidobacterium species (spp.) ... Cited by 62 - Related articles - BL Direct - All 3 versions
S Schenk, M Saberi, JM Olefsky - The Journal of Clinical …, 2008 - pubmedcentral.nih.gov Insulin resistance is a major metabolic feature of obesity and is a key factor in the etiology of
a number of diseases, including type 2 diabetes. In this review, we discuss potential mechanisms
by which brief nutrient excess and obesity lead to insulin resistance and propose that ... Cited by 47 - Related articles - All 12 versions
- ►ahajournals.org V Bourlier, A Zakaroff-Girard, A Miranville, S De Barros, … - Circulation, 2008 - Am Heart Assoc Methods and Results— The present study, performed on human subcutaneous AT, showed that
ATMs from lean to overweight individuals are composed of distinct macrophage subsets based
on the expression of several cell surface markers: CD45, CD14, CD31, CD44, HLA-DR, ... Cited by 41 - Related articles - All 6 versions
LK Heilbronn, LV Campbell - Current Pharmaceutical Design, 2008 - ingentaconnect.com Abstract: Obesity was first described as a low-grade inflammatory condition more than a decade
ago. However, it is only relatively re- cently that obese individuals have been described with
increased macrophage infiltration of adipose tissue, as well as an increase in the number ... Cited by 36 - Related articles - BL Direct - All 2 versions
E Seki, DA Brenner - Hepatology, 2008 - interscience.wiley.com Toll-like receptors (TLRs) are pattern recognition receptors that recognize pathogen-associated
molecular patterns and signal through adaptor molecules, myeloid differentiation factor 88
(MyD88), Toll/IL-1 receptor domain containing adaptor protein (TIRAP), Toll/IL-1 receptor ... Cited by 33 - Related articles - All 2 versions
- ►mayoclinicproceedings.com JK DiBaise, H Zhang, MD Crowell, R … - Mayo Clinic …, 2008 - mayoclinproc.highwire.org Obesity results from alterations in the body's regulation of energy intake, expenditure, and
storage. Recent evidence, primarily from investigations in animal models, suggests that the gut
microbiota affects nutrient acquisition and energy regulation. Its composition has also ... Cited by 31 - Related articles - BL Direct - All 8 versions
- ►fasebj.org M Membrez, F Blancher, M Jaquet, R Bibiloni, PD Cani, … - The FASEB Journal, 2008 - FASEB Recent data suggest that the gut microbiota plays a significant role in fat accumulation.
However, it is not clear whether gut microbiota is involved in the pathophysiology of type 2
diabetes. To assess this issue, we modulated gut microbiota via antibiotics administration ... Cited by 29 - Related articles - All 6 versions
- ►nutrition.org MO Weickert, AFH Pfeiffer - Journal of Nutrition, 2008 - Am Soc Nutrition A high dietary fiber (DF) intake is emphasized in the recommendations of most diabetes and
nutritional associations. It is accepted that viscous and gel-forming properties of soluble DF inhibit
macronutrient absorption, reduce postprandial glucose response, and beneficially ... Cited by 30 - Related articles - All 3 versions
C Erridge, T Attina, CM Spickett, DJ … - American Journal of …, 2007 - Am Soc Nutrition 2 Supported by British Heart Foundation Junior Fellowship (FS/03/97; to CE) and by a grant from
the Scottish Executive Chief Scientist Office (CZG/1/121). Strain NCTC 13114 was donated by
Ian Poxton, University of Edinburgh. ... Background: Bacterial endotoxin is a potently ... Cited by 28 - Related articles - BL Direct - All 6 versions