- ►nih.gov MS Sandhu, DM Waterworth, SL Debenham, E … - The Lancet, 2008 - Elsevier We used genome-wide association data from up to 11 685 participants with
measures of circulating LDL-cholesterol concentrations across five studies,
including data for 293 461 autosomal single nucleotide polymorphisms (SNPs) ... Cited by 77 - Related articles - All 8 versions
K Kirchhoff, F Machicao, A Haupt, SA Schäfer, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Variation within six novel genetic loci has been
reported to confer risk of type 2 diabetes and may be associated with beta cell
dysfunction. We investigated whether these polymorphisms are also ... Cited by 38 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] JC Florez, AK Manning, J Dupuis, J McAteer, … - Diabetes, 2007 - Am Diabetes Assoc Page 1. A 100K Genome-Wide Association Scan for Diabetes and Related Traits in the
Framingham Heart Study Replication and Integration With Other Genome-Wide ... Cited by 33 - Related articles - BL Direct - All 4 versions
JC Florez - Diabetologia, 2008 - Springer Abstract Although type 2 diabetes has been traditionally understood as a
metabolic disorder initiated by insulin resistance, it has recently become
apparent that an impairment in insulin secretion contributes to its mani- ... Cited by 31 - Related articles - BL Direct - All 3 versions
- ►kuleuven.be [PDF] N Bouatia-Naji, G Rocheleau, L Van Lommel, K … - Science, 2008 - sciencemag.org Page 1. DOI: 10.1126/science.1156849 , 1085 (2008); 320 Science et al. Nabila
Bouatia-Naji, Associated with Fasting Plasma Glucose Levels ... Cited by 30 - Related articles - BL Direct - All 11 versions
- ►prsjournal.net MN Weedon - Diabetic Medicine, 2007 - prsjournal.net After many years of frustratingly limited success, the genetic architecture of
Type 2 diabetes is finally being uncovered. Recent genome-wide association
studies have identified novel genes predisposing to Type 2 diabetes, which ... Cited by 26 - Related articles - Cached - BL Direct - All 5 versions
JRB Perry, TM Frayling - Current Opinion in Clinical Nutrition & Metabolic Care, 2008 - journals.lww.com Recent findings: Recent genome-wide association studies have provided an
important resource for furthering our understanding of type 2 diabetes disease
mechanisms. Genes previously unsuspected of playing a role in diabetes are ... Cited by 17 - Related articles - All 2 versions
- ►onlinejacc.org SB Damani, EJ Topol - Journal of the American College of Cardiology, 2007 - Elsevier Coronary artery disease (CAD) remains the number one cause of death in
industrialized countries despite our collective efforts to minimize attributable
risk from known contributors to CAD such as hypertension, dyslipidemia, and ... Cited by 16 - Related articles - BL Direct - All 20 versions
S Cauchi, H Choquet, R Gutiérrez-Aguilar, F … - Obesity, 2008 - nature.com In white European populations, we found that the rs7903146 T allele was more
associated with T2D in 3,547 non-obese individuals (odds ratio (OR) = 1.88
(1.69–2.10)) than in 1,110 class III obese subjects (OR = 1.24 ... Cited by 18 - Related articles - All 2 versions
S Cauchi, P Froguel - Current Diabetes Reports, 2008 - Springer After two decades of limited success, the genetic architecture of type 2
diabetes (T2D) is finally being revealed. Within only 2 years, an avalanche of
studies identified several genes expressed in pancreatic ß cells and ... Cited by 16 - Related articles - BL Direct - All 2 versions
