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Scholar Results 1 - 10 of about 44 citing Kolak: Adipose tissue inflammation and increased ceramide content characterize subjects with.... (0.07 sec) 

Fatty liver: a novel component of the metabolic syndrome

- ahajournals.org
A Kotronen, H Yki-Jarvinen - Arteriosclerosis, Thrombosis, and …, 2008 - Am Heart Assoc
Although the epidemic of obesity has been accompanied by an increase in the prevalence of
the metabolic syndrome, not all obese develop the syndrome and even lean individuals can
be insulin resistant. Both lean and obese insulin resistant individuals have an excess of ...
Cited by 82 - Related articles - All 6 versions

Gene expression in human NAFLD

- physiology.org
D Greco, A Kotronen, J Westerbacka, O … - American Journal of …, 2008 - Am Physiological Soc
Despite the high prevalence of nonalcoholic fatty liver disease (NAFLD), little is known of its pathogenesis
based on study of human liver samples. By the use of Affymetrix GeneChips (17,601 genes),
we investigated gene expression in the human liver of subjects with extreme steatosis ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Adipose macrophage infiltration is associated with insulin resistance and vascular …

- ahajournals.org
CM Apovian, S Bigornia, M Mott, MR Meyers, … - … , and vascular biology, 2008 - Am Heart Assoc
Methods and Results— We collected subcutaneous abdominal fat in 77 obese subjects (BMI
30 kg/m 2 ) and quantified adipose macrophage population using targeted
immunohistochemistry. Brachial artery vasodilator function was examined using high- ...
Cited by 19 - Related articles - All 8 versions

Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal …

- geyseco.info [PDF] 
G Targher, F Marra, G Marchesini - Diabetologia, 2008 - Springer
Abstract Non-alcoholic fatty liver disease (NAFLD), comprising a spectrum of conditions ranging
from pure steatosis to steatohepatitis and cirrhosis, has reached epidemic proportions and represents
the most common cause of chronic liver disease in the community. The prevalence of ...
Cited by 16 - Related articles - All 3 versions

The metabolic syndrome as a concept of adipose tissue disease


E Oda - Hypertension Research, 2008 - nature.com
The metabolic syndrome is a constellation of interrelated metabolic risk factors that appear to
directly promote the development of diabetes and cardiovascular disease. However, in
2005, the American Diabetes Association and the European Association for the Study of ...
Cited by 14 - Related articles - All 3 versions

Informatics and computational strategies for the study of lipids


L Yetukuri, K Ekroos, A Vidal-Puig, M Orešič - Molecular BioSystems, 2008 - rsc.org
Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered
us with the tools that afford studies of lipidomes at the systems level. However, these techniques
pose a number of challenges for lipidomic raw data processing, lipid informatics, and the ...
Cited by 13 - Related articles - Cached - BL Direct - All 4 versions

NASH predicts plasma inflammatory biomarkers independently of visceral fat in …


G Targher, L Bertolini, S Rodella, G Lippi, M Franchini, … - Obesity, 2008 - nature.com
We assessed the differential contribution of nonalcoholic steatohepatitis (NASH) and visceral
adiposity to nontraditional cardiovascular risk biomarkers in adult men. We enrolled 45
consecutive, overweight, male patients with biopsy-proven NASH, 45 overweight male ...
Cited by 13 - Related articles - All 3 versions

Reducing glycosphingolipid content in adipose tissue of obese mice restores …


M van Eijk, J Aten, N Bijl, R Ottenhoff, CPAA van … - PLoS One, 2009 - pubmedcentral.nih.gov
Adipose tissue is a critical mediator in obesity-induced insulin resistance. Previously we have
demonstrated that pharmacological lowering of glycosphingolipids and subsequently GM3 by
using the iminosugar AMP-DNM, strikingly improves glycemic control. Here we studied ...
Cited by 7 - Related articles - All 6 versions

Insulin regulation of MCP-1 in human adipose tissue of obese and lean women

- physiology.org
J Westerbacka, A Corner, M Kolak, J … - American Journal of …, 2008 - Am Physiological Soc
CCL2 (MCP-1, monocyte chemoattractant protein 1) and CCL3 (MIP-1 , macrophage inflammatory
protein 1 ) are required for macrophage infiltration in adipose tissue. Insulin increases CCL2
expression in adipose tissue and in serum more in insulin-resistant obese than in insulin- ...
Cited by 6 - Related articles - BL Direct - All 4 versions

Insulin resistance, inflammation, and non-alcoholic fatty liver disease


H Tilg, AR Moschen - Trends in Endocrinology & Metabolism, 2008 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), the major cause of abnormal liver function in the western
world, is often associated with obesity and diabetes. In obese individuals, fat accumulation in
the abdominal region affects both lipid and glucose metabolism, and a liver loaded with ...
Cited by 14 - Related articles - All 5 versions


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