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Scholar Results 1 - 10 of about 13 citing Liu: The SUMO conjugating enzyme Ubc9 is a regulator of GLUT4 turnover and targeting to the.... (0.06 sec) 

Functional role of sortilin in myogenesis and development of insulin-responsive …


M Ariga, T Nedachi, H Katagiri, M Kanzaki - Journal of Biological Chemistry, 2008 - ASBMB
Sortilin has been implicated in the formation of insulin-responsive GLUT4 storage vesicles in
adipocytes by regulating sorting events between the trans-Golgi-network and endosomes. We
herein show that sortilin serves as a potent myogenic differentiation stimulator for C2C12 ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Caveolin-1 Loss of Function Accelerates Glucose Transporter 4 and Insulin …


E Gonzalez-Munoz, C Lopez-Iglesias, M Calvo, M … - Endocrinology, 2009 - Endocrine Soc
Caveolae are a specialized type of lipid rafts that are stabilized by oligomers of caveolin
protein. Caveolae are particularly enriched in adipocytes. Here we analyzed the effects of
caveolin-1 knockdown and caveolae ablation on adipocyte function. To this end, we ...
Cited by 1 - Related articles - All 3 versions

Intracellular Retention and Insulin-Stimulated Mobilization of GLUT4 Glucose …


BR Rubin, JS Bogan - Vitamins & Hormones, 2009 - Elsevier
An insulin-regulated aminopeptidase that cotraffics with GLUT4, IRAP, is required for basal GSV
retention and insulin-stimulated mobilization. TUG and Ubc9 bind GLUT4, and likely retain GSVs
within unstimulated cells. These proteins may be components of a retention receptor, ...
Cited by 1 - Related articles - All 2 versions

The Roles of SUMO in Metabolic Regulation


DD Anderson, PJ Stover - SUMO Regulation of Cellular Processes, 2009 - Springer
Abstract Protein modification with the small ubiquitin-related modifier (SUMO) can affect protein
function, enzyme activity, protein-protein interactions, protein stability, protein targeting and cellular
localization. SUMO influences the func- tion and/or regulation of metabolic enzymes ...
Related articles - All 2 versions

Posttranslational regulation of Abcc2 expression by SUMOylation system


S Minami, K Ito, M Honma, Y Ikebuchi, N … - American Journal of …, 2009 - Am Physiological Soc
The ATP-binding cassette transporter family C 2 (Abcc2) is a member of efflux transporters involved
in the biliary excretion of organic anions from hepatocytes. Posttranslational regulation of Abcc2
has been implicated, although the molecular mechanism is not fully understood. In the ...
Related articles - All 3 versions

Self-assembly of Glut4 Storage Vesicles during Differentiation of 3T3-L1 …

- jbc.org
J Shi, G Huang, KV Kandror - Journal of Biological Chemistry, 2008 - ASBMB
Glut4 storage vesicles (GSVs) represent translocation-competent vesicular carriers in fat and
skeletal muscle cells that deliver Glut4 to the plasma membrane in response to insulin
stimulation. GSVs include three major cargo proteins: Glut4, insulin-responsive ...
Related articles - All 3 versions

SUM04-Encoded Genetic Susceptibility to Type 1 Diabetes


J Zhong, P Yang, F Gong, CY Wang - SUMO Regulation of Cellular …, 2009 - books.google.com
Chapter 16 SUM04-Encoded Genetic Susceptibility to Type 1 Diabetes Jixin Zhong, Ping
Yang, Feili Gong, and Cong-Yi Wang Abstract Susceptibility to type 1 diabetes (T1D) is determined
by interactions of multiple genes with environmental triggers. Thus far, more than 20 T1D ...
Related articles

Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O- …


MS Macauley, DJ Vocadlo - BBA-General Subjects, 2009 - Elsevier
The O-GlcNAc modification is found on many nucleocytoplasmic proteins. The dynamic nature
of O-GlcNAc, which in some ways is reminiscent of phosphorylation, has enabled investigators
to modulate the stoichiometry of O-GlcNAc on proteins in order to study its function. ...
Related articles - All 2 versions

Daxx functions as a scaffold of a protein assembly constituted by GLUT4, JNK1 and …


VS Lalioti, S Vergarajauregui, Y Tsuchiya, … - Journal of Cellular …, 2009 - interscience.wiley.com
We have previously reported the physical interaction between Daxx, the adaptor protein that
mediates activation of the Jun amino-terminal kinase (JNK), and GLUT4, the insulin-dependent
glucose transporter, interaction that involves their C-domains. Co-immunoprecipitation ...
Related articles - All 3 versions

SUMO4-Encoded Genetic Susceptibility to Type 1 Diabetes


J Zhong, P Yang, F Gong, CY Wang - Springer
Abstract Susceptibility to type 1 diabetes (T1D) is determined by interactions of multiple genes
with environmental triggers. Thus far, more than 20 T1D sus- ceptibility regions have been suggested
from genetic studies by employing either genome-wide or candidate gene approaches. ...
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