- ►nih.gov VA Narkar, M Downes, RT Yu, E Embler, YX Wang, E … - Cell, 2008 - Elsevier The benefits of endurance exercise on general health make it desirable to identify orally active
agents that would mimic or potentiate the effects of exercise to treat metabolic diseases. Although
certain natural compounds, such as reseveratrol, have endurance-enhancing activities, ... Cited by 75 - Related articles - All 12 versions
KS Röckl, CA Witczak, LJ Goodyear - IUBMB life, 2008 - educ.uidaho.edu Summary Physical activity elicits physiological responses in skeletal muscle that result in a number
of health benefits, in particular in disease states, such as type 2 diabetes. An acute bout of
exer- cise/muscle contraction improves glucose homeostasis by increasing skeletal ... Cited by 14 - Related articles - View as HTML - All 4 versions
E Breen, K Tang, M Olfert, A Knapp, P … - High Altitude Medicine & …, 2008 - liebertonline.com Breen, Ellen, Kechun Tang, Mark Olfert, Amy Knapp, and Peter Wagner. High Alt. Med. Biol.
9:158-166, 2008.— Long-term exposure of humans and many mammals to hypoxia leads to
the activation of several cellular mech- anisms within skeletal muscles that compensate ... Cited by 13 - Related articles - All 3 versions
KA Zwetsloot, LM Westerkamp, BF Holmes, … - The Journal of …, 2008 - Physiological Soc 5′-AMP-activated protein kinase (AMPK) is a metabolic fuel sensor that monitors cellular energy
charge, while the vasculature is important for maintaining cellular energy homeostasis. Mice
with muscle-specific inactive AMPK (AMPK DN) were used to investigate if AMPK ... Cited by 10 - Related articles - All 7 versions
HJ Koh, J Brandauer, LJ Goodyear - Current Opinion in Clinical …, 2008 - journals.lww.com Introduction The AMP-activated protein kinase (AMPK) was first identified as a Ser/Thr kinase
that inactivates key enzymes involved in lipid and cholesterol biosynthesis [1]. In skeletal
muscle, several lines of evidence support a role of AMPK in the regulation of glucose ... Cited by 9 - Related articles - BL Direct - All 3 versions
- ►nih.gov Z Arany - Current opinion in genetics & development, 2008 - Elsevier Skeletal muscle adapts to physiological demands by altering a number of programs of gene
expression, including those driving mitochondrial biogenesis, angiogenesis, and fiber
composition. Recently, the PGC-1 transcriptional coactivators have emerged as key ... Cited by 7 - Related articles - All 4 versions
PM Garcia-Roves, ME Osler, MH Holmström, JR … - Journal of Biological …, 2008 - ASBMB AMP-activated protein kinase (AMPK) is a heterotrimeric complex, composed of a catalytic subunit
(α) and two regulatory subunits (β and γ), that works as a cellular energy sensor. The existence
of multiple heterotrimeric complexes provides a molecular basis for the multiple roles of ... Cited by 5 - Related articles - All 3 versions
B Viollet, Y Athea, R Mounier, B Guigas, E … - Frontiers in …, 2009 - pubmedcentral.nih.gov AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine protein
kinase, has been proposed to function as a 'fuel gauge' to monitor cellular energy status in response
to nutritional environmental variations. AMPK system is a regulator of energy balance ... Cited by 5 - Related articles - All 3 versions
M Fulco, V Sartorelli - Cell cycle (Georgetown, Tex.), 2008 - pubmedcentral.nih.gov The ability to adapt and respond to nutrients is an ancient cellular function, conserved from unicellular
to the most complex multicellular organisms, including mammals. Mammals adapt to changes
in nutritional status through the modulation of tissue-specific metabolic pathways so as to ... Cited by 5 - Related articles - All 5 versions
- ►jbc.org AA Wooldridge, CN Fortner, B Lontay, T Akimoto, … - Journal of Biological …, 2008 - ASBMB In vivo protein kinases A and G (PKA and PKG) coordinately phosphorylate a broad range of
substrates to mediate their various physiological effects. The functions of many of these substrates
have yet to be defined genetically. Herein we show a role for smoothelin-like protein 1 ( ... Cited by 4 - Related articles - All 4 versions
