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Scholar Results 1 - 10 of about 17 citing Ishikawa: Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody. (0.10 sec) 

Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells


H Ishikawa, K Tanaka, Y Maeda, Y Aiba, A … - Clinical and Experimental Immunology, 2008 - pubmedcentral.nih.gov
When oral tolerance was induced in either specific pathogen-free (SPF) or
germ-free (GF) mice, ovalbumin (OVA) feeding before immunization induced oral
tolerance successfully in SPF mice. On the other hand, OVA-specific ...
Cited by 10 - Related articles - All 6 versions

A shift from adaptive to innate immunity: a potential mechanism of disease progression in …


HL Weiner - Journal of neurology, 2008 - Springer
Multiple sclerosis is a progressive, disabling neurologi- cal disease which is
heterogeneous in terms of its origi- nal clinical presentation and its clinical
course.Approx- imately 85% of patients present initially with an acute ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Future research directions in multiple sclerosis therapies

- continuumwfn.com
BM Greenberg, PA Calabresi - Seminars in Neurology, 2008 - thieme-connect.com
The success of presently available injectable immunomodulatory therapies in
treating multiple sclerosis has led to heightened interest in finding even more
efficacious and better tolerated therapies. Several oral agents have shown ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25-LAP+ …

- jimmunol.org
HY Wu, FJ Quintana, HL Weiner - The Journal of Immunology, 2008 - Am Assoc Immnol
Lupus is an Ab-mediated autoimmune disease. One of the potential contributors to
the development of systemic lupus erythematosus is a defect in naturally
occurring CD4 + CD25 + regulatory T cells. Thus, the generation of ...
Cited by 8 - Related articles - All 4 versions

TGF-β–dependent suppressive function of Tregs requires wild-type levels of CD18 in a …


H Wang, T Peters, A Sindrilaru, D Kess, T … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov
Dysfunctional Tregs have been identified in individuals with psoriasis. However,
their role in the pathogenesis of the disease remains unclear. Here we explored
the effect of diminished CD18 (β 2 integrin) expression on the function of ...
Cited by 5 - Related articles - All 7 versions

The gut mucosa as a site for induction of regulatory T-cells


M Mizrahi, Y Ilan - Current Pharmaceutical Design, 2009 - ingentaconnect.com
Abstract: Regulatory T lymphocytes (Tregs) are specialized for immune
suppression and are important regulators of the immune response in various
settings. Tregs actively suppress enteroantigen-reactive cells and ...
Cited by 5 - Related articles - All 2 versions

IFN-γ and IL-4 Differentially Shape Metabolic Responses and Neuroprotective Phenotype of …


SK Garg, J Kipnis, R Banerjee - Journal of Neurochemistry, 2009 - interscience.wiley.com
Astrocytes can either exacerbate or ameliorate secondary degeneration at sites
of injury in the central nervous system but the contextual basis for eliciting
these opposing phenotypes is poorly understood. In this study, we ...
Cited by 1 - Related articles - All 3 versions

Oral tolerance: Can we make it work?


Y Ilan - Human Immunology, 2009 - Elsevier
Mucosal tolerance remains an attractive approach for the treatment of autoimmune
and inflammatory diseases. The agents used in these treatments lack toxicity,
can be easily administered, and enable the promotion of antigen-specific ...
Cited by 1 - Related articles - All 2 versions

The emerging role of the microbial-gastrointestinal-neural axis

- pagepress.org
PG McLean, AR Calver, DH Alpers, SM … - Gastroenterology Insights, 2009 - pagepress.org
The gastrointestinal tract and its associated mucosal immune system have been
extensively studied in the context of their involvement in disease processes,
both within the tract itself and in its associated organs. However, ...
Related articles - Cached - All 2 versions

Methods of modulating immunity


HL Weiner, MH Sayegh - US Patent App. 10/987,380, 2004 - Google Patents
Patent Application Publication Sep. 8,2005 Sheet 1 of 21 US 2005/0196395 Al
Figure 1 10 13 14 16 17 20 21 23 24 27 31 38 day post immunization Figure 2 3000
2500 2000 - Q_ 1500 - o 1000 500 - 0 PLP (in-vitro) 100
Related articles - All 10 versions


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