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Scholar Results 1 - 10 of about 19 citing Toyoda: Podocyte detachment and reduced glomerular capillary endothelial fenestration in.... (0.07 sec) 

Proteinuria in diabetic kidney disease: a mechanistic viewpoint


JA Jefferson, SJ Shankland, RH Pichler - Kidney International, 2008 - nature.com
Proteinuria is the hallmark of diabetic kidney disease (DKD) and is an independent risk factor
for both renal disease progression, and cardiovascular disease. Although the characteristic pathological
changes in DKD include thickening of the glomerular basement membrane and ...
Cited by 13 - Related articles - All 3 versions

[PDF] Podocyte-specific overexpression of the antioxidant metallothionein reduces …


S Zheng, EC Carlson, L Yang, PM Kralik, Y … - Journal of the American …, 2008 - Am Soc Nephrol
ABSTRACT Podocytes are critical components of the selective filtration barrier of the glomerulus
and are susceptible to oxidative damage. For investigation of the role of oxidative stress and
podocyte damage in diabetic nephropathy, transgenic mice that overexpress the ...
Cited by 10 - Related articles - All 5 versions

Failure to phosphorylate AKT in podocytes from mice with early diabetic …


T Tejada, P Catanuto, A Ijaz, JV Santos, X Xia, P … - Kidney International, 2008 - nature.com
Loss of podocytes by apoptosis characterizes the early stages of diabetic nephropathy. To examine
its mechanism we studied glomeruli and podocytes isolated from db/db mice with early diabetic
nephropathy and albuminuria. Phosphorylation of AKT (protein kinase B, a key survival ...
Cited by 7 - Related articles - BL Direct - All 4 versions

New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy


FC Brosius - Reviews in endocrine & metabolic disorders, 2008 - Springer
Abstract Progression of diabetic nephropathy (DN) is manifested by gradual scarring of both
the renal glomerulus and tubulointerstitial region. Over the past several years, the general understanding
of the pathogenic factors that lead to renal fibrosis in DN has expanded considerably. In ...
Cited by 6 - Related articles - All 3 versions

Diabetes and vessel wall remodelling: from mechanistic insights to regenerative …

- oxfordjournals.org
G Spinetti, N Kraenkel, C … - Cardiovascular …, 2008 - cardiovascres.oxfordjournals.org
Over the past two decades, extensive research has focused on arterial remodelling in both physiological
and pathological ageing. The concept now describes the growth as well as the rearrangement
of cellular components and extracellular matrix, resulting in either reduction or increase in ...
Cited by 6 - Related articles - All 4 versions

High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: …


N Rabbani, SS Alam, S Riaz, JR Larkin, MW Akhtar, T … - Diabetologia, 2009 - Springer
Page 1. SHORT COMMUNICATION High-dose thiamine therapy for patients with type 2 diabetes
and microalbuminuria: a randomised, double-blind placebo-controlled pilot study N. Rabbani &
SS Alam & S. Riaz & JR Larkin & MW Akhtar & T. Shafi & PJ Thornalley ...
Cited by 4 - Related articles - All 2 versions

Diabetes and chronic kidney disease: lessons from the Pima Indians


KV Lemley - Pediatric Nephrology, 2008 - Springer
Abstract Although diabetic nephropathy is a very rare cause of kidney failure during
childhood, the underlying events leading to progressive kidney injury begin during childhood
in many patients with type 1 diabetes mellitus (T1DM) and in increasing numbers of ...
Cited by 4 - Related articles - All 2 versions

Proteinuria as a surrogate outcome in CKD: report of a scientific workshop …

- zhshen.com.cn [PDF] 
AS Levey, D Cattran, A Friedman, WG Miller, J … - American Journal of …, 2009 - Elsevier
Changes in proteinuria have been suggested as a surrogate outcome for kidney disease progression
to facilitate the conduct of clinical trials. This report summarizes a workshop sponsored by the
National Kidney Foundation and US Food and Drug Administration (FDA) with the ...
Cited by 3 - Related articles - All 22 versions

Complications of type 1 diabetes: new molecular findings


A Stirban, P Rösen, D Tschoepe - Mount Sinai Journal of …, 2008 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 1 - Related articles - All 2 versions

Glomerular endothelial cell fenestrations: an integral component of the glomerular …


SC Satchell, F Braet - American Journal of Physiology- Renal …, 2009 - Am Physiological Soc
American Physiological Society. ISSN: 0363-6127, ESSN: 1522-1466. Visit our website at
(monthly) by the American Physiological Society, 9650 Rockville Pike, Bethesda MD
20814-3991. Copyright © 2005 by the respective cells and vasculature, as well as to the ...
Cited by 2 - Related articles - All 3 versions


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