K Miyake, Y Horikawa, K Hara, K Yasuda, H Osawa … - Journal of Human …, 2008 - Springer Abstract Transcription factor 7-like 2 (TCF7L2) has been shown to be associated with type 2
diabetes mellitus in multiple ethnic groups. Regarding the Asian population, Horikoshi et al.
(Diabetologia 50:747–751, 2007) and Hayashi et al. (Diabetologia 50:980–984, 2007) ... Cited by 21 - Related articles - BL Direct - All 3 versions
DJ Margolis, O Hofstad, BL Strom - … and drug safety, 2008 - pubmedcentral.nih.gov This is a retrospective cohort study of diabetic patients at least 40 years of age treated in general
practices participating in The Health Information Network (THIN) data system between 2002
and 2006. Our primary outcome was serious atherosclerotic vascular disease of the heart. Cited by 15 - Related articles - All 5 versions
S Cauchi, P Froguel - Current Diabetes Reports, 2008 - Springer After two decades of limited success, the genetic architecture of type 2 diabetes (T2D) is finally
being revealed. Within only 2 years, an avalanche of studies identified several genes expressed
in pancreatic ß cells and involved in the control of insulin secretion, such as transcription ... Cited by 16 - Related articles - BL Direct - All 2 versions
LA Donnelly, CNA Palmer, AL Whitley, CC … - Pharmacogenetics …, 2008 - journals.lww.com Background Apolipoprotein E (APOE) genotypes have been associated with variations in
plasma–lipid levels and with response to statins, although the influence of APOE on the response
to statins remains controversial, especially in patients with diabetes. We sought to ... Cited by 10 - Related articles - BL Direct - All 7 versions
MI McCarthy, E Zeggini - Trends in Pharmacological Sciences, 2007 - Elsevier Type 2 diabetes is a complex, multifactorial disease, for which genetic and environmental factors
jointly determine susceptibility. Disentangling the genetic aetiology of Type 2 diabetes has proven
a challenging task, rewarded, until recently, with only limited success. However, the field ... Cited by 10 - Related articles - All 3 versions
- ►geyseco.info [PDF] JC Florez - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Evidence Synthesis: As many as 17 genetic loci have been convincingly associated with type
2 diabetes; 14 of these were not previously known, and most of them were unsuspected. The
associated polymorphisms are common in populations of European descent but have ... Cited by 12 - Related articles - All 4 versions
A Korner, W Kiess, M Stumvoll, P … - Frontiers of hormone …, 2008 - content.karger.com Abstract Obesity results from the complex interaction of environmental factors that act on a genetic
back- ground that determines the susceptibility to obesity. The identification of such obesity susceptibility
genes can provide important insights into the mechanism underlying this condition. While ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org MI McCarthy, AT Hattersley - Diabetes, 2008 - Am Diabetes Assoc Genetic factors for many decades have been known to play a critical role in the etiology of
diabetes, but it has been only recently that the specific genes have been identified. The identification
of the underlying molecular genetics opens the possibility for understanding the genetic ... Cited by 9 - Related articles - All 4 versions
- ►diabetesjournals.org MO Goodarzi, JI Rotter - Diabetes, 2007 - Am Diabetes Assoc Given that susceptibility to type 2 diabetes appears in large measure due to genetic makeup,
investigators have spent years of effort trying to identify genes that influence type 2 diabetes
risk. An important goal of gene identification is to improve our understanding of the ... Cited by 4 - Related articles - BL Direct - All 3 versions
