J Bain, L Plater, M Elliott, N Shpiro, CJ … - The Biochemical Journal, 2007 - pubmedcentral.nih.gov The specificities of 65 compounds reported to be relatively specific inhibitors
of protein kinases have been profiled against a panel of 70–80 protein
kinases. On the basis of this information, the effects of compounds that we ... Cited by 222 - Related articles - BL Direct - All 6 versions
- ►physiology.org K Sakamoto, GD Holman - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Vesicular traffic of the glucose transporter GLUT4 occurs in response to
insulin, muscle contraction, and metabolic stimuli that lead to changes in the
energy status of the cell. These stimuli are associated with linked kinase ... Cited by 22 - Related articles - All 6 versions
- ►nih.gov JR Bayascas, S Wullschleger, K Sakamoto, JM … - Molecular and Cellular Biology, 2008 - Am Soc Microbiol PDK1 activates a group of kinases, including protein kinase B (PKB)/Akt, p70
ribosomal S6 kinase (S6K), and serum and glucocorticoid-induced protein kinase
(SGK), that mediate many of the effects of insulin as well as other ... Cited by 15 - Related articles - BL Direct - All 13 versions
- ►jbc.org CJ Green, O Goransson, GS Kular, NR Leslie, … - Journal of Biological Chemistry, 2008 - ASBMB Protein kinase B (PKB)/Akt has been strongly implicated in the insulin-dependent
stimulation of GLUT4 translocation and glucose transport in skeletal muscle and
fat cells. Recently an allosteric inhibitor of PKB (Akti) that selectively ... Cited by 9 - Related articles - All 3 versions
V Calleja, M Laguerre, PJ Parker, B Larijani - PLoS Biol, 2009 - biology.plosjournals.org Protein kinase B (PKB/Akt) belongs to the AGC superfamily of related
serine/threonine protein kinases. It is a key regulator downstream of various
growth factors and hormones and is involved in malignant transformation and ... Cited by 6 - Related articles - Cached - All 7 versions
AR Cameron, S Anton, L Melville, NP Houston … - Journal of Anatomy - interscience.wiley.com In vertebrates and invertebrates, relationships between diet and health are
controlled by a conserved signalling pathway responsive to insulin-like ligands.
In invertebrate models for example, forkhead transcription factor family O ... Cited by 7 - Related articles - BL Direct - All 3 versions
SB Widenmaier, AV Sampaio, TM Underhill, … - Journal of Biological Chemistry, 2009 - ASBMB Therapeutics based on the actions of the incretin hormones, glucagon-like
peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), have
recently been introduced for the treatment of type 2 diabetes mellitus. The ... Cited by 4 - Related articles - All 3 versions
RW Hunter, MT Harper, I Hers - Journal of Thrombosis and Haemostasis, 2008 - interscience.wiley.com Summary. Background: The role of PKB in platelet function is poorly defined due
to the lack of genuinely selective small-molecule inhibitors and limiting
genetic models. Recently, a selective, non-ATP-competitive PKB inhibitor, ... Cited by 2 - Related articles - All 3 versions
RW Hunter, C MacKintosh, I Hers - Journal of Biological Chemistry, 2009 - ASBMB The elevation of [cAMP] i is an important mechanism of platelet inhibition and
is regulated by the opposing activity of adenylyl cyclase and phosphodiesterase
(PDE). In this study, we demonstrate that a variety of platelet agonists, ... Cited by 1 - Related articles - All 3 versions
