S Palomba, A Falbo, F Zullo, F Orio Jr - Endocrine Reviews, 2009 - Endocrine Soc Metformin is an insulin sensitizer widely used for the treatment of patients
affected by type 2 diabetes mellitus. Because many women with polycystic ovary
syndrome (PCOS) are insulin resistant, metformin was introduced in clinical ... Cited by 13 - Related articles - All 6 versions
M Doblado, KH Moley - Current Opinion in Endocrinology, Diabetes and …, 2007 - journals.lww.com Purpose of review: It has been known for decades that diabetic women have
somewhat decreased fertility and that their offspring have an increased risk of
being born with developmental abnormalities. We review results from studies ... Cited by 6 - Related articles - BL Direct - All 3 versions
ES Jungheim, KH Moley - Seminars in reproductive medicine, 2008 - thieme-connect.com Whereas the importance of close monitoring and tight glycemic control in
diabetic pregnancies cannot be ignored, the growing body of knowledge
surrounding the different effects of diabetes mellitus on the earliest ... Cited by 4 - Related articles - BL Direct - All 8 versions
- ►reproduction-online.org E Louden, MM Chi, KH Moley - Reproduction, 2008 - Soc Reprod Fertility Maternal insulin resistance results in poor pregnancy outcomes. In vivo and in
vitro exposure of the murine blastocyst to high insulin or IGF1 results in the
down-regulation of the IGF1 receptor (IGF1R). This in turn leads to ... Cited by 3 - Related articles - All 5 versions
MA Velazquez, J Zaraza, A Oropeza, R Webb … - Reproduction, 2009 - Soc Reprod Fertility IGF1 plays an important role in bovine follicular growth, acquisition of oocyte
competence and embryo viability. Current data also indicate a critical role for
IGF1 in both the ovarian response and the embryo yield following the ... Cited by 1 - Related articles - All 3 versions
- ►reproduction-online.org ST Kim, KH Moley - Reproduction, 2008 - Soc Reprod Fertility The objective of this study was to determine whether sperm quality,
fertilization capacity, and subsequent embryo development are altered in
diabetic male mice and whether differences in facilitative glucose ... Cited by 1 - Related articles - All 3 versions