- ►jimmunol.org N Perez, S Karumuthil-Melethil, R Li, BS … - The Journal of …, 2008 - Am Assoc Immnol Costimulatory ligands CD80 and CD86 have different binding preferences and affinities to their
receptors, CD28 and CTLA-4. Earlier, we demonstrated that CD80 binds to CTLA-4 with higher affinity
and has a role in suppressing T ... Cited by 5 - Related articles - All 4 versions
CEB Couri, JC Voltarelli - Arquivos Brasileiros de Endocrinologia & …, 2008 - SciELO Brasil Type 1 diabetes mellitus is the result of the autoimmune response against pancreatic b-cell(s). At
the time of clinical diagnosis near 70% of b-cell mass is been destroyed as a consequence of the
auto-destruction that begins months ... Cited by 5 - Related articles - Cached - All 4 versions
Q Leng, Y Nie, Y Zou, J Chen - BMC immunology, 2008 - biomedcentral.com Type I diabetes (TID) is an autoimmune disease resulting from destruction of the insulin-producing
β-cells by autoreactive T cells. Studies have shown that polymorphisms of chemokine CXCL12 gene are
linked to TID in humans. In ... Cited by 2 - Related articles - Cached - All 6 versions
S Karumuthil-Melethil, N Perez, R Li, C … - The Journal of …, 2008 - Am Assoc Immnol Studies have suggested a correlation between the decline in infectious diseases and increase in the
incidence of type 1 diabetes (T1D) in developed countries. Pathogens influence the disease outcome
through innate immune receptors ... Cited by 2 - Related articles - All 2 versions
P Monti, AK Heninger, E Bonifacio - Current Diabetes Reports, 2009 - Springer Autoreactive T cells play a major role in the patho- genesis of type 1 diabetes mellitus (T1DM) and
are considered a major target of immunomodulatory strategies aimed at preventing or delaying the
disease onset. However, the T-cell ... Cited by 1 - Related articles - All 2 versions
F Alfinito, M Sica, L Luciano, R Della Pepa … - British Journal of …, 2009 - interscience.wiley.com The myelodysplastic syndromes (MDS) are clonal disorders characterised by ineffective haematopoiesis
with high risk of leukaemia progression. The relevance of immune-dysregulation for emergence,
dominance and progression of ... Related articles - All 2 versions
F Ezquer, M Ezquer, V Simon, F Pardo, A Yañez, D … - Biology of Blood and …, 2009 - Elsevier Twenty-five to 40% of diabetic patients develop diabetic nephropathy, a clinical syndrome that
comprises renal failure and increased risk of cardiovascular disease. It represents the major cause
of chronic kidney disease and is ... Related articles - All 4 versions
CEB Couri, JC Voltarelli - sld.cu Type 1 diabetes mellitus is the result of the autoimmune response against pancreatic b-cell(s). At
the time of clinical diagnosis near 70% of b-cell mass is been destroyed as a consequence of the
auto-destruction that begins months ... Related articles - Cached