AJ Ren, ZF Guo, YK Wang, LG Wang, WZ Wang … - Biochemical and Biophysical Research …, 2008 - Elsevier Obestatin is a bioactive peptide encoded by the same gene that encodes ghrelin.
Our aim was to investigate the effect of obestatin on insulin secretion. We
evaluated the effects of obestatin on insulin secretion from rat islet ... Cited by 9 - Related articles - All 4 versions
- ►cell.com O Gualillo, F Lago, C Dieguez - Trends in Pharmacological Sciences, 2008 - Elsevier The acyltransferase that catalyzes ghrelin octanoylation has recently been
identified as ghrelin O-acyltransferase (GOAT). GOAT belongs to a family of
membrane-bound O-acyltransferases (MBOATs). GOAT covalently links a medium ... Cited by 6 - Related articles - All 4 versions
EM Egido, R Hernández, J Marco, RA … - Regulatory Peptides, 2009 - Elsevier Obestatin is a 23-amino acid peptide derived from preproghrelin, purified from
stomach extracts and detected in peripheral plasma. In contrast to ghrelin,
obestatin has been reported to inhibit appetite and gastric motility. ... Cited by 2 - Related articles - All 3 versions
BP Cummings, EK Digitale, KL Stanhope, JL … - … Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc The prevalence of type 2 diabetes (T2DM) is increasing, creating a need for T2DM
animal models for the study of disease pathogenesis, prevention, and treatment.
The purpose of this project was to develop a rat model of T2DM that more ... Cited by 1 - Related articles - All 3 versions
R Gómez, F Lago, JJ Gómez-Reino, O … - Expert Opin. Ther. Targets, 2009 - informahealthcare.com Background: Obesity is the major cause of type 2 diabetes. In the mid 1990s
interest in adipose tissue was revived by the discovery of leptin. The
association of obesity and diabetes emphasizes their shared ... Related articles - All 6 versions
MI Mladenov, KL Hristov, DZ Dimitriova, R … - Acta Physiologica, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Related articles - All 3 versions
R Jain, E Lammert - Diabetes, Obesity and Metabolism, 2009 - interscience.wiley.com Cell–cell communication within any given tissue is an important aspect of
correct organ function. The islets of Langerhans forming the endocrine pancreas
are composed of α-, β-, δ-, ε- and PP-cells, and interactions between ... Related articles - All 2 versions
KA Bennett, CJ Langmead, A Wise, G Milligan - Molecular Pharmacology, 2009 - ASPET Some growth hormone secretagogues act as agonists at the ghrelin receptor and
have been described as "ago-allosteric" ligands because of an ability to also
modulate the maximum efficacy and potency of ghrelin (Holst et al., 2005 Go ... Related articles - All 4 versions
E Ghigo, R Granata, LAJ Van Der, 2008 - freepatentsonline.com An isolated polypeptide comprising any amino acid fragment of unacylated ghrelin
or any analog thereof, wherein the polypeptide has an activity selected from the
group consisting of a) decreasing blood glucose levels; b) increasing ... Related articles - All 3 versions
J Sågetorp - uu.diva-portal.org Dissertation presented at Uppsala University to be publicly examined in B21,
BMC, Husargatan 3, Uppsala, Saturday, March 21, 2009 at 09:15 for the degree of
Doctor of Philosophy (Faculty of Medicine). The examination will be ... Related articles - View as HTML - All 2 versions