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Scholar Results 1 - 10 of about 21 citing Navaratna: Proteolytic degradation of VE-cadherin alters the blood-retinal barrier in diabetes. (0.08 sec) 

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and …


Y Wallez, P Huber - BBA-Biomembranes, 2008 - Elsevier
The endothelium is located at the inner side of all vessel types and is
constituted by a monolayer of endothelial cells. Interendothelial junctions
contain complex junctional structures, namely adherens junctions (AJ), ...
Cited by 32 - Related articles - All 3 versions

Matrix metalloproteinases as modulators of inflammation

- nih.gov
AM Manicone, JK McGuire - Seminars in Cell and Developmental Biology, 2008 - Elsevier
An increased expression of members of the matrix metalloproteinase (MMP) family
of enzymes is seen in almost every human tissue in which inflammation is
present. Through the use of models of human disease in mice with targeted ...
Cited by 25 - Related articles - All 4 versions

ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of …

- ahajournals.org
B Schulz, J Pruessmeyer, T Maretzky, A Ludwig … - Circulation Research, 2008 - Am Heart Assoc
Vascular endothelial (VE)-cadherin is the major adhesion molecule of endothelial
adherens junctions. It plays an essential role in controlling endothelial
permeability, vascular integrity, leukocyte transmigration, and ...
Cited by 17 - Related articles - All 4 versions

Gelatinases mediate neutrophil recruitment in vivo: evidence for stimulus specificity and a …

- jleukbio.org
CA Reichel, M Rehberg, P Bihari, CM Moser, … - Journal of Leukocyte Biology, 2008 - Soc Leukocyte Biology
In the present study, the role of gelatinases [matrix metalloproteinase-2 and -9
(MMP-2 and -9)] for leukocyte rolling, adherence, and transmigration was
analyzed in the mouse cremaster muscle under different inflammatory ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Vasoinhibins prevent retinal vasopermeability associated with diabetic retinopathy in rats …


C García, J Aranda, E Arnold, S Thébault, Y … - The Journal of clinical investigation, 2008 - pubmedcentral.nih.gov
Increased retinal vasopermeability contributes to diabetic retinopathy, the
leading cause of blindness in working-age adults. Despite clinical progress,
effective therapy remains a major need. Vasoinhibins, a family of peptides ...
Cited by 4 - Related articles - BL Direct - All 7 versions

Breaking the VE-cadherin bonds

- arxiv.org [PDF] 
J Gavard - FEBS Letters, 2009 - Elsevier
Exchanges between the blood compartment and the surrounding tissues require a
tight regulation by the endothelial barrier. Recent reports inferred that
VE-cadherin, an endothelial specific cell–cell adhesion molecule, plays a ...
Cited by 3 - Related articles - All 10 versions

A peptide inhibitor of the urokinase/urokinase receptor system inhibits alteration of the blood- …

- fasebj.org
D Navaratna, G Menicucci, J Maestas, R … - The FASEB Journal, 2008 - FASEB
One of the major complications of diabetes is the alteration of the
blood-retinal barrier, leading to retinal edema and consequent vision loss. The
aim of this study was to evaluate the role of the urokinase plasminogen ...
Cited by 1 - Related articles - All 5 versions

Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental …


LA Buhler, R Samara, E Guzman, CL Wilson, L … - BMC neuroscience, 2009 - pubmedcentral.nih.gov
Here we report that MMP-7-deficient (mmp7 -/- ) mice on the C57Bl/6 background
are resistant to EAE induced by myelin oligodendrocyte glycoprotein (MOG). Brain
sections from MOG-primed mmp7 -/- mice did not show signs of immune cell ...
Cited by 1 - Related articles - All 7 versions

Protective Effects of a Coumarin Derivative in Diabetic Rats


C Bucolo, KW Ward, E Mazzon, S Cuzzocrea, … - Investigative Ophthalmology & Visual Science, 2009 - ARVO
1 From the Department of Experimental and Clinical Pharmacology, School of
Medicine, University of Catania, Catania, Italy; 2 Global Preclinical R&D Bausch
& Lomb, Rochester, New York; 3 IRCCS Centro Neurolesi Bonino-Pulejo, ...
Related articles - All 3 versions

14 Vascular Permeability in Diabetic Retinopathy


DA Antonetti, HD VanGuilder, C Mao-Lin - Springer
A hallmark of diabetic retinopathy is increased vascular permeability. The
vasculature of the retina, which normally has tight control of the fluid and
blood components that enter the retina, becomes leaky in diabetes leading ...
Related articles


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