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Scholar Results 1 - 10 of about 15 citing Baschal: HLA-DPB1* 0402 protects against type 1A diabetes autoimmunity in the highest risk.... (0.07 sec) 

Defining the role of the MHC in autoimmunity: a review and pooled analysis


MMA Fernando, CR Stevens, EC Walsh, PL De … - PLOS …, 2008 - pubmedcentral.nih.gov
The major histocompatibility complex (MHC) is one of the most extensively studied regions in
the human genome because of the association of variants at this locus with autoimmune,
infectious, and inflammatory diseases. However, identification of causal variants within ...
Cited by 44 - Related articles - All 8 versions

The natural history of type 1A diabetes


GS Eisenbarth, J Jeffrey - Arquivos Brasileiros de Endocrinologia & …, 2008 - SciELO Brasil
Keywords: type 1 diabetes; Anti-islet autoimmunity; Autoantibodies; HlA, genetic ... RESuMO
A História do Diabetes Melito Tipo 1. Atualmente o desenvolvimento do diabetes melito tipo
1 A( imune mediado) pode ser predito através da determinação de quatro ...
Cited by 35 - Related articles - View as HTML - All 6 versions

Extreme genetic risk for type 1A diabetes in the post-genome era

- nih.gov
EE Baschal, GS Eisenbarth - Journal of autoimmunity, 2008 - Elsevier
A series of genes and loci influencing the genetic risk of type 1A (immune-mediated) diabetes
are now well characterized. These include genes of the major histocompatibility complex
(MHC), polymorphisms 5′ of the insulin gene, and PTPN22, as well as more recently ...
Cited by 13 - Related articles - All 3 versions

Analysis of single nucleotide polymorphisms identifies major type 1A diabetes …

- diabetesjournals.org
TA Aly, EE Baschal, MM Jahromi, MS Fernando, SR … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We found evidence for an association with type 1A diabetes (rs1233478, P = 1.6
× 10 −23 , allelic odds ratio 2.0) in the UBD/MAS1L region, telomeric of the classic MHC. We
also observed over 99% conservation for up to 9 million nucleotides between ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in …

- rupress.org
M Oresic, S Simell, M Sysi-Aho, K Nanto- … - Journal of Experimental …, 2008 - jem.rupress.org
The risk determinants of type 1 diabetes, initiators of autoimmune response, mechanisms regulating
progress toward β cell failure, and factors determining time of presentation of clinical diabetes
are poorly understood. We investigated changes in the serum metabolome prospectively ...
Cited by 11 - Related articles - All 6 versions

Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 …


MC Eike, T Becker, K Humphreys, M Olsson, BA Lie - 2008 - nature.com
The major histocompatibility complex (MHC) is known to harbour genetic risk factors for type
1 diabetes (T1D) additional to the class II determinants HLA-DRB1, -DQA1 and -DQB1, but strong
linkage disequilibrium (LD) has made efforts to establish their location difficult. This study ...
Cited by 8 - Related articles - All 4 versions

Analysis of SNPs identifies major type 1A diabetes locus telomeric of the MHC

- diabetesjournals.org [PDF] 
TA Aly, EE Baschal, MM Jahromi, MS Fernando, SR … - Diabetes, 2007 - Am Diabetes Assoc
Theresa A. Aly, MD, PhD 1,2* , Erin E. Baschal, BA 1,2* , Mohamed M. Jahromi, PhD 1 , Maria
S. ... Fernando, BS 1 , Sunanda R. Babu, PhD 1 , Tasha E. Fingerlin, PhD 2,3 , Adam
Kretowski, MD 1,4 , ... Henry A Erlich, PhD 5 , Pamela R. Fain, PhD 1,2 , Marian J. ...
Cited by 5 - Related articles - All 4 versions

HLA-DPB1 associations differ between DRB1* 03 positive anti-Jo-1 and anti-PM- …


H Chinoy, D Payne, KV Poulton, N Fertig, Z … - …, 2009 - Br Soc Rheumatology
1 Centre for Integrated Genomic Medical Research, University of Manchester, Manchester, 2
The University of Manchester Rheumatic Diseases Centre, Salford Royal NHS Foundation
Trust, Salford, 3 Transplantation Laboratory, Manchester Royal Infirmary, Manchester, ...
Cited by 1 - Related articles - All 3 versions

[CITATION] Pathogenesis of type 1 diabetes mellitus


G SUSCEPTIBILITY, DOFI DEFICIENCY
Related articles - All 2 versions

Genetic Epidemiology of Type 1 Diabetes


GS Eisenbarth, TA Aly - Epidemiology of Pediatric and Adolescent …, 2008 - books.google.com
Genetic Epidemiology of Type 1 Diabetes George S. Eisenbarth and Theresa A. Aly Barbara
Davis Center for Childhood Diabetes and Human Medical Genetics Program, University of Colorado
at Denver and Health Sciences Center, Aurora, Colorado, USA INTRODUCTION ...
Related articles - All 2 versions


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