MMA Fernando, CR Stevens, EC Walsh, PL De … - PLOS …, 2008 - pubmedcentral.nih.gov The major histocompatibility complex (MHC) is one of the most extensively studied regions in
the human genome because of the association of variants at this locus with autoimmune,
infectious, and inflammatory diseases. However, identification of causal variants within ... Cited by 44 - Related articles - All 8 versions
GS Eisenbarth, J Jeffrey - Arquivos Brasileiros de Endocrinologia & …, 2008 - SciELO Brasil Keywords: type 1 diabetes; Anti-islet autoimmunity; Autoantibodies; HlA, genetic ... RESuMO
A História do Diabetes Melito Tipo 1. Atualmente o desenvolvimento do diabetes melito tipo
1 A( imune mediado) pode ser predito através da determinação de quatro ... Cited by 35 - Related articles - View as HTML - All 6 versions
- ►nih.gov EE Baschal, GS Eisenbarth - Journal of autoimmunity, 2008 - Elsevier A series of genes and loci influencing the genetic risk of type 1A (immune-mediated) diabetes
are now well characterized. These include genes of the major histocompatibility complex
(MHC), polymorphisms 5′ of the insulin gene, and PTPN22, as well as more recently ... Cited by 13 - Related articles - All 3 versions
- ►diabetesjournals.org TA Aly, EE Baschal, MM Jahromi, MS Fernando, SR … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We found evidence for an association with type 1A diabetes (rs1233478, P = 1.6
× 10 −23 , allelic odds ratio 2.0) in the UBD/MAS1L region, telomeric of the classic MHC. We
also observed over 99% conservation for up to 9 million nucleotides between ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►rupress.org M Oresic, S Simell, M Sysi-Aho, K Nanto- … - Journal of Experimental …, 2008 - jem.rupress.org The risk determinants of type 1 diabetes, initiators of autoimmune response, mechanisms regulating
progress toward β cell failure, and factors determining time of presentation of clinical diabetes
are poorly understood. We investigated changes in the serum metabolome prospectively ... Cited by 11 - Related articles - All 6 versions
MC Eike, T Becker, K Humphreys, M Olsson, BA Lie - 2008 - nature.com The major histocompatibility complex (MHC) is known to harbour genetic risk factors for type
1 diabetes (T1D) additional to the class II determinants HLA-DRB1, -DQA1 and -DQB1, but strong
linkage disequilibrium (LD) has made efforts to establish their location difficult. This study ... Cited by 8 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] TA Aly, EE Baschal, MM Jahromi, MS Fernando, SR … - Diabetes, 2007 - Am Diabetes Assoc Theresa A. Aly, MD, PhD 1,2* , Erin E. Baschal, BA 1,2* , Mohamed M. Jahromi, PhD 1 , Maria
S. ... Fernando, BS 1 , Sunanda R. Babu, PhD 1 , Tasha E. Fingerlin, PhD 2,3 , Adam
Kretowski, MD 1,4 , ... Henry A Erlich, PhD 5 , Pamela R. Fain, PhD 1,2 , Marian J. ... Cited by 5 - Related articles - All 4 versions
H Chinoy, D Payne, KV Poulton, N Fertig, Z … - …, 2009 - Br Soc Rheumatology 1 Centre for Integrated Genomic Medical Research, University of Manchester, Manchester, 2
The University of Manchester Rheumatic Diseases Centre, Salford Royal NHS Foundation
Trust, Salford, 3 Transplantation Laboratory, Manchester Royal Infirmary, Manchester, ... Cited by 1 - Related articles - All 3 versions
[CITATION] Pathogenesis of type 1 diabetes mellitus
GS Eisenbarth, TA Aly - Epidemiology of Pediatric and Adolescent …, 2008 - books.google.com Genetic Epidemiology of Type 1 Diabetes George S. Eisenbarth and Theresa A. Aly Barbara
Davis Center for Childhood Diabetes and Human Medical Genetics Program, University of Colorado
at Denver and Health Sciences Center, Aurora, Colorado, USA INTRODUCTION ... Related articles - All 2 versions