SE Allan, R Broady, S Gregori, ME Himmel, N … - Immunological Reviews, 2008 - pt.wkhealth.com Acknowledgements: We thank Paul Orban for critical reading of the manuscript.
The authors' own research was supported by grants from the Canadian Institutes
for Health Research (CIHR), the National Cancer Institute of Canada, the ... Cited by 22 - Related articles - All 6 versions
- ►j-talk.com R Spolski, M Kashyap, C Robinson, Z Yu, WJ … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences IL-21 is a pleiotropic type I cytokine that shares the common cytokine receptor
γ chain and plays important roles for normal Ig production, terminal B cell
differentiation to plasma cells, and Th17 differentiation. IL-21 is ... Cited by 18 - Related articles - All 8 versions
E Jaeckel, N Mpofu, N Saal, MP Manns - Hormone and Metabolic Research, 2008 - thieme-connect.com Beta-cell specific autoreactive T cells can be found in patients with type I
diabetes (T1D) and in healthy controls. They are usually controlled by a network
of regulatory mechanisms including CD4+CD25+Foxp3+ regulatory T cells ... Cited by 9 - Related articles - BL Direct - All 2 versions
- ►pnas.org AM D'Alise, V Auyeung, M Feuerer, J Nishio, J … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences FoxP3 + regulatory T cells (Tregs) protect against autoimmunity, type 1 diabetes
(T1D) in particular, prompting the hypothesis that a deficiency in Tregs is a
critical determinant of diabetes susceptibility in NOD mice. However, tests ... Cited by 8 - Related articles - All 7 versions
SG Zheng - International Journal of Clinical and Experimental …, 2008 - pubmedcentral.nih.gov Foxp3+T regulatory cell (Treg) subsets play a crucial role in the maintenance of
immune homeostasis against self-antigen. The lack or dysfunction of these cells
is responsible for the pathogenesis and development of many autoimmune ... Cited by 6 - Related articles - All 5 versions
DB Rainbow, L Esposito, SK Howlett, KM … - Biochemical Society transactions, 2008 - pubmedcentral.nih.gov The MHC region remains the major genetic determinant causing T1D in humans and
NOD mice [1, 2] and the identification of non-MHC genes contributing T1D
susceptibility has made significant progress. Of particular note, in 2007 ... Cited by 6 - Related articles - BL Direct - All 9 versions
CA Dendrou, LS Wicker - Journal of Clinical Immunology, 2008 - Springer Abstract Although the interleukin-2 (IL-2)/IL-2R signal- ing pathway has been
the focus of numerous studies, certain aspects of its molecular regulation are
not well characterized, especially in non-T cells, and a more complete ... Cited by 3 - Related articles - All 2 versions
E Sgouroudis, CA Piccirillo - Diabetes/Metabolism Reviews - interscience.wiley.com In recent years, there has been a revival of the concept of CD4 + regulatory T
(T reg ) cells as being a central control point in various immune responses,
including autoimmune responses and immunity to transplants, allergens, ... Cited by 5 - Related articles - All 2 versions
RR Dietert - Current Drug Safety, 2008 - ingentaconnect.com Abstract: Developmental immunotoxicity (DIT) recently emerged as a significant
concern for drug safety and was the topic of several recent scientific forums in
Europe, North America and Asia. The heightened concern is based on several ... Cited by 2 - Related articles - All 3 versions
